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Stock Option Plans and Warrants to Purchase Common Stock (Details 1) (Stock Options [Member], USD $)
12 Months Ended
Dec. 31, 2012
Dec. 31, 2011
Stock Options [Member]
   
Summary of options/warrants activity    
Beginning Balance 1,544,242 1,308,056
Granted 100,000 523,344
Exercised    (79,844)
Forfeited (186,518) (207,314)
Ending Balance 1,457,724 1,544,242
Beginning Balance, weighted average options/warrants exercise price $ 3.75 $ 4.84
Granted, weighted average options/warrants exercise price $ 0.30 $ 1.68
Exercised, weighted average options/warrants exercise price    $ 3.18
Forfeited, weighted average options exercise price $ 6.22 $ 1.88
Ending Balance, weighted average options/warrants exercise price $ 3.19 $ 3.75