Stock Option Plans and Warrants to Purchase Common Stock (Tables)

12 Months Ended

Dec. 31, 2012

Stock Options [Member]

Share-based Compensation Arrangement by Share-based Payment Award [Line Items]

Summary of option and warrant activity

	Options			Weighted Average Options Exercise Price
Balance at December 31, 2010		1,308,056			4.84
Granted		523,344			1.68
Exercised		(79,844	)		3.18
Forfeited		(207,314	)		1.88
Balance at December 31, 2011		1,544,242		$	3.75
Granted		100,000			0.30
Exercised		-			-
Forfeited		(186,518	)		6.22
Balance at December 31, 2012		1,457,724		$	3.19

Weighted-average range of exercise prices for options and warrants outstanding and exercisable

Price Range	Weighted Average Remaining Contractual Life in Years		Outstanding  Options		Exercisable  Options
$0.30-$2.20		7.9		738,300		542,050
$2.80-$4.10		8.1		186,674		151,283
$4.64-$8.60		5.9		426,500		391,891
$9.40-$11.60		4.1		97,500		97,500
$18.00-$25.60		0.7		8,750		8,750
Total		7.0		1,457,724		1,191,474

Warrant [Member]

Share-based Compensation Arrangement by Share-based Payment Award [Line Items]

Summary of option and warrant activity

	Warrants			Weighted Average Warrant Exercise Price
Balance at December 31, 2010		2,703,819		$	4.40
Granted		4,750			3.85
Exercised		-			-
Expired/Cancelled		(7,000	)		0.66
Balance at December 31, 2011		2,701,569		$	4.40
Granted		774,873			0.56
Exercised		-			-
Expired/Cancelled		(633,104	)		5.40
Balance at December 31, 2012		2,843,338		$	3.13

Weighted-average range of exercise prices for options and warrants outstanding and exercisable

Price Range	Weighted Average Remaining Contractual Life in Years		Outstanding  Warrants		Exercisable Warrants
$.53-$2.00		5.0		777,373		777,373
$2.80-$3.96		1.1		1,103,202		1,103,202
$5.00-$6.06		2.2		962,763		962,763
Total		2.5		2,843,338		2,843,338

Equity incentive plan [Member]

Share-based Compensation Arrangement by Share-based Payment Award [Line Items]

Summary of option and warrant activity

	December 31,
	2012			2011
Shares available for grant at beginning of year		60,692			396,223
Increase in shares available for the plan		-			-
Options granted		(100,000	)		(523,344	)
Options forfeited or expired		169,019			187,813
Shares available for grant at end of year		129,711			60,692