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Proc-Type: 2001,MIC-CLEAR
Originator-Name: webmaster@www.sec.gov
Originator-Key-Asymmetric:
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MIC-Info: RSA-MD5,RSA,
 VA9vsLiKadX/zc2O3y7ko5GkoaxdeCkSWqs6WyZwflBaKVyyUXcU4B61s6uy2YgS
 6FRZ8LlUYXQlFOUijjxKXQ==

<SEC-DOCUMENT>0001209191-03-022630.txt : 20030923
<SEC-HEADER>0001209191-03-022630.hdr.sgml : 20030923
<ACCEPTANCE-DATETIME>20030923173905
ACCESSION NUMBER:		0001209191-03-022630
CONFORMED SUBMISSION TYPE:	4
PUBLIC DOCUMENT COUNT:		1
CONFORMED PERIOD OF REPORT:	20030915
FILED AS OF DATE:		20030923

ISSUER:		

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			DOR BIOPHARMA INC
		CENTRAL INDEX KEY:			0000812796
		STANDARD INDUSTRIAL CLASSIFICATION:	PHARMACEUTICAL PREPARATIONS [2834]
		IRS NUMBER:				411505029
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	BUSINESS ADDRESS:	
		STREET 1:		28101 N. BALLARD DR. SUITE F
		CITY:			LAKE FOREST
		STATE:			IL
		ZIP:			60045
		BUSINESS PHONE:		847-573-8990

	MAIL ADDRESS:	
		STREET 1:		28101 N. BALLARD DR. SUITE F
		CITY:			LAKE FOREST
		STATE:			IL
		ZIP:			60045

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	ENDOREX CORP
		DATE OF NAME CHANGE:	19960916

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	IMMUNOTHERAPEUTICS INC
		DATE OF NAME CHANGE:	19920703

REPORTING-OWNER:	

	OWNER DATA:	
		COMPANY CONFORMED NAME:			MYRIANTHOPOULOS EVAN
		CENTRAL INDEX KEY:			0001050955

	FILING VALUES:
		FORM TYPE:		4
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	000-16929
		FILM NUMBER:		03906682

	BUSINESS ADDRESS:	
		STREET 1:		DISCOVERY LABORATORIES INC
		STREET 2:		509 MADISON AVE 14TH FLOOR
		CITY:			NEW YORK
		STATE:			NY
		ZIP:			10022
		BUSINESS PHONE:		2122234504

	MAIL ADDRESS:	
		STREET 2:		509 MADISON AVE 14TH FL
		CITY:			NEW YORK
		STATE:			NY
		ZIP:			10022
</SEC-HEADER>
<DOCUMENT>
<TYPE>4
<SEQUENCE>1
<FILENAME>boc79744-01em.xml
<DESCRIPTION>MAIN DOCUMENT DESCRIPTION
<TEXT>
<XML>
<?xml version="1.0"?><ownershipDocument><schemaVersion>X0201</schemaVersion>    <documentType>4</documentType><periodOfReport>2003-09-15</periodOfReport><notSubjectToSection16>0</notSubjectToSection16><issuer><issuerCik>0000812796</issuerCik><issuerName>DOR BIOPHARMA INC</issuerName>        <issuerTradingSymbol>DOR</issuerTradingSymbol></issuer><reportingOwner><reportingOwnerId><rptOwnerCik>0001050955</rptOwnerCik><rptOwnerName>MYRIANTHOPOULOS EVAN</rptOwnerName></reportingOwnerId><reportingOwnerAddress><rptOwnerStreet1>1691 MICHIGAN AVENUE</rptOwnerStreet1><rptOwnerStreet2>SUITE 435</rptOwnerStreet2><rptOwnerCity>MIAMI</rptOwnerCity><rptOwnerState>FL</rptOwnerState><rptOwnerZipCode>33139</rptOwnerZipCode><rptOwnerStateDescription></rptOwnerStateDescription></reportingOwnerAddress><reportingOwnerRelationship><isDirector>1</isDirector><isOfficer>0</isOfficer><isTenPercentOwner>0</isTenPercentOwner><isOther>0</isOther></reportingOwnerRelationship></reportingOwner><derivativeTable><derivativeTransaction><securi
tyTitle><value>Stock Options (right to buy)</value></securityTitle><conversionOrExercisePrice><value>.900</value></conversionOrExercisePrice><transactionDate><value>2003-09-15</value></transactionDate><transactionCoding><transactionFormType>4</transactionFormType><transactionCode>A</transactionCode><equitySwapInvolved>0</equitySwapInvolved></transactionCoding><transactionAmounts><transactionShares><value>50000</value></transactionShares><transactionPricePerShare><value>.900</value></transactionPricePerShare><transactionAcquiredDisposedCode><value>A</value></transactionAcquiredDisposedCode></transactionAmounts><exerciseDate><value>2003-09-15</value></exerciseDate><expirationDate><value>2013-09-15</value></expirationDate><underlyingSecurity><underlyingSecurityTitle><value>Common Stock</value></underlyingSecurityTitle><underlyingSecurityShares><value>50000</value></underlyingSecurityShares></underlyingSecurity><postTransactionAmounts><sharesOwnedFollowingTransaction><value>50000</value></sharesOwnedFollowingTra
nsaction></postTransactionAmounts><ownershipNature><directOrIndirectOwnership><value>D</value></directOrIndirectOwnership></ownershipNature></derivativeTransaction><derivativeTransaction><securityTitle><value>Stock Warrants</value></securityTitle><conversionOrExercisePrice><value>.8756</value></conversionOrExercisePrice><transactionDate><value>2003-09-15</value></transactionDate><transactionCoding><transactionFormType>4</transactionFormType><transactionCode>A</transactionCode><equitySwapInvolved>0</equitySwapInvolved></transactionCoding><transactionAmounts><transactionShares><value>77694</value></transactionShares><transactionPricePerShare><value>.8756</value></transactionPricePerShare><transactionAcquiredDisposedCode><value>A</value></transactionAcquiredDisposedCode></transactionAmounts><exerciseDate><value>2003-09-15</value></exerciseDate><expirationDate><value>2008-09-15</value></expirationDate><underlyingSecurity><underlyingSecurityTitle><value>Common Stock</value></underlyingSecurityTitle><underlyingSec
urityShares><value>120888</value></underlyingSecurityShares></underlyingSecurity><postTransactionAmounts><sharesOwnedFollowingTransaction><value>120888</value></sharesOwnedFollowingTransaction></postTransactionAmounts><ownershipNature><directOrIndirectOwnership><value>D</value></directOrIndirectOwnership></ownershipNature></derivativeTransaction></derivativeTable><ownerSignature><signatureName>Evan Myrianthopoulos</signatureName><signatureDate>2003-09-15</signatureDate></ownerSignature></ownershipDocument>

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</DOCUMENT>
</SEC-DOCUMENT>
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