-----BEGIN PRIVACY-ENHANCED MESSAGE-----
Proc-Type: 2001,MIC-CLEAR
Originator-Name: webmaster@www.sec.gov
Originator-Key-Asymmetric:
 MFgwCgYEVQgBAQICAf8DSgAwRwJAW2sNKK9AVtBzYZmr6aGjlWyK3XmZv3dTINen
 TWSM7vrzLADbmYQaionwg5sDW3P6oaM5D3tdezXMm7z1T+B+twIDAQAB
MIC-Info: RSA-MD5,RSA,
 IsMgY9Ip5QMyvP5nqFyd7PMHT1lsOEV8rLbi112UERvKvVdcGMAgzEmOe+w3p7qK
 gazbGcsiwzAhOTa9PmtlCw==

<SEC-DOCUMENT>0001140361-05-003507.txt : 20050510
<SEC-HEADER>0001140361-05-003507.hdr.sgml : 20050510
<ACCEPTANCE-DATETIME>20050510165445
ACCESSION NUMBER:		0001140361-05-003507
CONFORMED SUBMISSION TYPE:	3
PUBLIC DOCUMENT COUNT:		1
CONFORMED PERIOD OF REPORT:	20050504
FILED AS OF DATE:		20050510
DATE AS OF CHANGE:		20050510

REPORTING-OWNER:	

	OWNER DATA:	
		COMPANY CONFORMED NAME:			Madison T J
		CENTRAL INDEX KEY:			0001326651

	FILING VALUES:
		FORM TYPE:		3
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	000-16929
		FILM NUMBER:		05817535

	BUSINESS ADDRESS:	
		BUSINESS PHONE:		305-534-3383

	MAIL ADDRESS:	
		STREET 1:		1691 MICHIGAN AVE, SUITE 435
		CITY:			MIAMI
		STATE:			FL
		ZIP:			33139

ISSUER:		

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			DOR BIOPHARMA INC
		CENTRAL INDEX KEY:			0000812796
		STANDARD INDUSTRIAL CLASSIFICATION:	PHARMACEUTICAL PREPARATIONS [2834]
		IRS NUMBER:				411505029
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	BUSINESS ADDRESS:	
		STREET 1:		1691 MICHIGAN AVE.
		STREET 2:		SUITE 435
		CITY:			MIAMI
		STATE:			FL
		ZIP:			33139
		BUSINESS PHONE:		305-534-3383

	MAIL ADDRESS:	
		STREET 1:		1691 MICHIGAN AVE.
		STREET 2:		SUITE 435
		CITY:			MIAMI
		STATE:			FL
		ZIP:			33139

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	ENDOREX CORP
		DATE OF NAME CHANGE:	19960916

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	IMMUNOTHERAPEUTICS INC
		DATE OF NAME CHANGE:	19920703
</SEC-HEADER>
<DOCUMENT>
<TYPE>3
<SEQUENCE>1
<FILENAME>doc1.xml
<DESCRIPTION>FORM 3
<TEXT>
<XML>
<?xml version="1.0"?>
<ownershipDocument>

    <schemaVersion>X0202</schemaVersion>

    <documentType>3</documentType>

    <periodOfReport>2005-05-04</periodOfReport>

    <noSecuritiesOwned>0</noSecuritiesOwned>

    <issuer>
        <issuerCik>0000812796</issuerCik>
        <issuerName>DOR BIOPHARMA INC</issuerName>
        <issuerTradingSymbol>DOR</issuerTradingSymbol>
    </issuer>

    <reportingOwner>
        <reportingOwnerId>
            <rptOwnerCik>0001326651</rptOwnerCik>
            <rptOwnerName>Madison T J</rptOwnerName>
        </reportingOwnerId>
        <reportingOwnerAddress>
            <rptOwnerStreet1>1691 MICHIGAN AVE</rptOwnerStreet1>
            <rptOwnerStreet2>SUITE 435</rptOwnerStreet2>
            <rptOwnerCity>MIAMI</rptOwnerCity>
            <rptOwnerState>FL</rptOwnerState>
            <rptOwnerZipCode>33139</rptOwnerZipCode>
            <rptOwnerStateDescription></rptOwnerStateDescription>
        </reportingOwnerAddress>
        <reportingOwnerRelationship>
            <isDirector>1</isDirector>
            <isOfficer>0</isOfficer>
            <isTenPercentOwner>0</isTenPercentOwner>
            <isOther>0</isOther>
            <officerTitle></officerTitle>
            <otherText></otherText>
        </reportingOwnerRelationship>
    </reportingOwner>

    <derivativeTable>
        <derivativeHolding>
            <securityTitle>
                <value>Stock Options (right to buy)</value>
            </securityTitle>
            <conversionOrExercisePrice>
                <value>.33</value>
            </conversionOrExercisePrice>
            <exerciseDate>
                <value>2005-05-04</value>
            </exerciseDate>
            <expirationDate>
                <value>2015-05-04</value>
            </expirationDate>
            <underlyingSecurity>
                <underlyingSecurityTitle>
                    <value>Common Stock</value>
                </underlyingSecurityTitle>
                <underlyingSecurityShares>
                    <value>50000</value>
                </underlyingSecurityShares>
            </underlyingSecurity>
            <ownershipNature>
                <directOrIndirectOwnership>
                    <value>D</value>
                </directOrIndirectOwnership>
                <natureOfOwnership>
                    <value></value>
                </natureOfOwnership>
            </ownershipNature>
        </derivativeHolding>
    </derivativeTable>

    <remarks></remarks>

    <ownerSignature>
        <signatureName>/s/ T. Jerome Madison</signatureName>
        <signatureDate>2005-05-10</signatureDate>
    </ownerSignature>
</ownershipDocument>
</XML>
</TEXT>
</DOCUMENT>
</SEC-DOCUMENT>
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