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Assumptions Used in Estimating Fair Value of Stock Options Granted (Detail)
12 Months Ended
Dec. 31, 2018
Dec. 31, 2017
Dec. 31, 2016
Share Based Compensation Arrangement By Share Based Payment Award Fair Value Assumptions And Methodology [Abstract]      
Expected term (years) 5 years 10 months 13 days 5 years 6 months 3 days 5 years 11 months 15 days
Volatility 81.00% 79.00% 86.00%
Risk-free interest rate 2.54% 1.99% 1.39%