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Assumptions Used in Estimating Fair Value of Stock Options Granted (Detail)
3 Months Ended 9 Months Ended
Sep. 30, 2016
Sep. 30, 2015
Sep. 30, 2016
Sep. 30, 2015
Share Based Compensation Arrangement By Share Based Payment Award Fair Value Assumptions And Methodology [Abstract]        
Expected term 5 years 10 months 24 days 6 years 5 years 9 months 18 days 5 years 8 months 12 days
Volatility 86.58% 86.17% 85.48% 88.98%
Risk-free interest rate 1.30% 1.70% 1.32% 1.60%