Note 17 - Subsequent Events (Details Textual) - USD ($)				1 Months Ended	12 Months Ended
	Mar. 21, 2023	Mar. 15, 2023	Oct. 28, 2022	Feb. 28, 2023	Dec. 31, 2022		Dec. 31, 2021	Mar. 06, 2023	Jan. 31, 2023	Oct. 31, 2022	Jul. 25, 2022	Dec. 31, 2020	Jul. 23, 2019
Class of Warrant or Right, Granted During Period (in shares)			326,171		326,171	[1]	0
Warrants and Rights Outstanding, Term (Year)			5 years
Common Stock, Par or Stated Value Per Share					$ 0.001		$ 0.001
Class of Warrant or Right, Outstanding					340,689		14,518					24,814
Proceeds from Issuance or Sale of Equity, Total			$ 2,055,000
Class of Warrant or Right, Exercised During Period (in shares)					64,286		(0)
Pre-funded Units Warrant [Member]
Class of Warrant or Right, Granted During Period (in shares)					64,286
Warrant Amendment Agreement [Member]
Class of Warrant or Right, Exercise Price of Warrants or Rights										$ 6.30
Convertible Debt [Member] | Boyalife Asset Holding II [Member]
Debt Instrument, Convertible, Conversion Price					$ 6.30		$ 81.00
Notes Payable, Related Parties					$ 5,777,000		$ 9,245,000
The July 2019 Note [Member] | Convertible Debt [Member]
Debt Instrument, Convertible, Conversion Price					$ 6.30		$ 40.95			$ 6.30	$ 9.45		$ 81.00
Subsequent Event [Member]
Stock Issued During Period, Shares, New Issues		125,000
Common Stock, Par or Stated Value Per Share		$ 0.001
Proceeds from Issuance or Sale of Equity, Total		$ 2,600,000
Subsequent Event [Member] | Pre-funded Units Warrant [Member]
Class of Warrant or Right, Outstanding		946,429
Share Price		$ 2.80
Class of Warrant or Right, Number of Securities Called by Warrants or Rights		1,071,429
Class of Warrant or Right, Exercise Price of Warrants or Rights		$ 2.65
Subsequent Event [Member] | Warrant Amendment Agreement [Member]
Class of Warrant or Right, Number of Securities Called by Warrants or Rights		158,731
Class of Warrant or Right, Exercise Price of Warrants or Rights		$ 2.65
Class of Warrant or Right, Exercised During Period (in shares)	158,731
Subsequent Event [Member] | Conversion of January 2019 Amended Notes to Common Stock [Member]
Debt Conversion, Converted Instrument, Shares Issued				215,000
Subsequent Event [Member] | Convertible Debt [Member] | Boyalife Asset Holding II [Member]
Notes Payable, Related Parties								$ 7,278,000
Subsequent Event [Member] | The July 2019 Note [Member] | Convertible Debt [Member]
Debt Instrument, Convertible, Conversion Price									$ 2.87
Short Term, Gross				$ 397,000
Subsequent Event [Member] | The July 2019 Note [Member] | Convertible Debt [Member] | Conversion of January 2019 Amended Notes to Common Stock [Member]
Debt Conversion, Original Debt, Amount				$ 603,000

[1] Warrants are subject to stockholder approval and will remain outstanding but unvested until the Company receives such approval. Subsequent to December 31, 2022, the Company’s stockholders approved the warrants.