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Note 11 - Stockholders' Equity - Anti-dilutive Securities (Details) - shares
12 Months Ended
Dec. 31, 2022
Dec. 31, 2021
Common stock equivalents of convertible promissory notes and accrued interest (in shares) 1,872,843 199,310
Convertible Debt Securities [Member]    
Common stock equivalents of convertible promissory notes and accrued interest (in shares) 1,525,751 176,907
Warrant, Other [Member]    
Common stock equivalents of convertible promissory notes and accrued interest (in shares) 340,689 14,518
Share-Based Payment Arrangement, Option [Member]    
Common stock equivalents of convertible promissory notes and accrued interest (in shares) 6,403 7,885