Note 11 -Stockholders' Equity - Warrant Activity (Details) - $ / shares		12 Months Ended
	Oct. 28, 2022	Dec. 31, 2022		Dec. 31, 2021	Dec. 31, 2020
Balance (in shares)		14,518		24,814
Balance, exercise price (in dollars per share)		$ 313.71		$ 1,677.28
Warrants, weighted average remaining contract term (Year)		3 months 21 days		1 year 5 months 8 days	5 months 26 days
Warrants granted (in shares)	326,171	326,171	[1]	0
Warrants granted, weighted average exercise price (in dollars per share)		$ 6.30	[1]	$ 0
Warrants exercised (in shares)		(64,286)		0
Warrants exercised, weighted average exercise price (in dollars per share)		$ 0.045		$ 0
Warrants expired/canceled (in shares)		0		(10,296)
Warrants expired/canceled, weighted average exercise price (in dollars per share)		$ 0		$ 3,600.00
Balance (in shares)		340,689		14,518	24,814
Balance, exercise price (in dollars per share)		$ 19.40		$ 313.71	$ 1,677.28
Exercisable, shares (in shares)		14,518
Exercisable, weighted average exercise price (in dollars per share)		$ 313.71
Exercisable, weighted average remaining contractual term (Year)		5 months 8 days
Pre-funded Units Warrant [Member]
Warrants granted (in shares)		64,286
Warrants granted, weighted average exercise price (in dollars per share)		$ 0.045

[1] Warrants are subject to stockholder approval and will remain outstanding but unvested until the Company receives such approval. Subsequent to December 31, 2022, the Company’s stockholders approved the warrants.