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Note 1 - Description of Business and Basis of Presentation (Details Textual)
3 Months Ended
Apr. 21, 2020
USD ($)
Jun. 04, 2019
Jan. 01, 2019
USD ($)
Mar. 31, 2019
USD ($)
Jun. 30, 2020
USD ($)
shares
Apr. 28, 2020
USD ($)
Dec. 31, 2019
USD ($)
shares
Nov. 26, 2019
USD ($)
Jun. 30, 2019
shares
Mar. 31, 2017
USD ($)
Stockholders' Equity Attributable to Noncontrolling Interest, Ending Balance         $ 316,000   $ 530,000      
Reorganization of Subsidiary and Related Change in Non-controlling Interest                  
Common Stock, Shares Authorized (in shares) | shares         350,000,000   350,000,000   350,000,000  
Notes Payable, Current, Total         $ 287,000        
Notes Payable, Noncurrent, Total         359,000   1,000,000      
Cash and Cash Equivalents, at Carrying Value, Ending Balance         6,984,000   3,157,000      
Working Capital         8,059,000          
Retained Earnings (Accumulated Deficit), Ending Balance         (247,971,000)   $ (236,932,000)      
Paycheck Protection Program CARES Act [Member]                    
Proceeds from Issuance of Long-term Debt, Total $ 646,000                  
Notes Payable, Current, Total 287,000                  
Notes Payable, Noncurrent, Total $ 359,000                  
Boyalife Investment Fund II, Inc. [Member] | Revolving Credit Facility [Member]                    
Line of Credit Facility, Maximum Borrowing Capacity         10,000,000         $ 10,000,000
Long-term Line of Credit, Total         $ 10,000,000 $ 10,000,000        
Reverse Stock Split [Member]                    
Stockholders' Equity Note, Stock Split, Conversion Ratio   10                
ImmuneCyte [Member]                    
Equity Method Investment, Ownership Percentage         18.79%     20.00%    
Line of Credit Facility, Maximum Borrowing Capacity               $ 1,000,000    
ImmuneCyte [Member] | HealthBanks Biotech [Member]                    
Equity Method Investment, Ownership Percentage         75.16%     80.00%    
Noncontrolling Interest [Member]                    
Reorganization of Subsidiary and Related Change in Non-controlling Interest     $ 2,843,000 $ 2,843,000            
CAR-TXpress [Member]                    
Noncontrolling Interest, Ownership Percentage by Parent     80.00%   80.00%          
Minority Interest Acquired Through Exchange     20.00%              
Stockholders' Equity Attributable to Noncontrolling Interest, Ending Balance     $ 1,100,000              
Noncontrolling Interest, Ownership Percentage by Noncontrolling Owners         20.00%          
ThermoGenesis [Member]                    
Noncontrolling Interest, Ownership Percentage by Parent     100.00%              
Ownership in Subsidiary Exchanged     20.00%              
Stockholders' Equity Attributable to Noncontrolling Interest, Ending Balance     $ (1,711,000)