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Note 3 - Related Party Transactions (Details Textual) - USD ($)
3 Months Ended 12 Months Ended
Mar. 12, 2018
Aug. 21, 2017
Mar. 31, 2019
Mar. 31, 2018
Dec. 31, 2018
Apr. 16, 2018
Apr. 01, 2018
Amortization of Debt Discount (Premium)     $ 586,000      
Interest Expense, Total     1,132,000 361,000      
Adjustments for New Accounting Principle, Early Adoption [Member] | Accounting Standards Update 2017-11 [Member]              
Debt Instrument, Unamortized Discount, Total     1,513,000       $ 7,200,000
Amortization of Debt Discount (Premium)     586,000        
Boyalife Investment Fund II, Inc. [Member] | Convertible Debt [Member]              
Debt Instrument, Convertible, Conversion Price         $ 0.18 $ 1.61  
Boyalife Investment Fund II, Inc. [Member] | Revolving Credit Facility [Member]              
Line of Credit Facility, Maximum Borrowing Capacity     10,000,000        
Proceeds from Long-term Lines of Credit     8,713,000   $ 7,200,000    
Line of Credit Facility, Remaining Borrowing Capacity     $ 1,287,000        
Debt Instrument, Interest Rate, Stated Percentage     22.00%        
Interest Expense, Total     $ 1,047,000 360,000      
Interest Payable     461,000   $ 1,513,000    
Boyalife W.S.N. [Member]              
Distributor Agreement Term   3 years          
Distributor Agreement, Renewal Term   2 years          
Revenue from Related Parties     $ 266,000 $ 226,000      
IncoCell [Member]              
Contract Development Revenue, Term 10 years