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Note 1 - Description of Business, Going Concern and Basis of Presentation (Details Textual) - USD ($)
1 Months Ended 6 Months Ended 12 Months Ended
Aug. 28, 2018
May 18, 2018
Mar. 28, 2018
Dec. 01, 2017
Aug. 03, 2016
Jun. 30, 2018
Dec. 31, 2017
Dec. 31, 2018
Jun. 30, 2017
Jul. 07, 2017
Stock Issued During Period, Shares, New Issues     609,636 898,402 600,000          
Common Stock, Par or Stated Value Per Share             $ 0.001 $ 0.001    
Shares Issued, Price Per Share     $ 2.27 $ 3 $ 4.10          
Class of Warrant or Right, Issued During Period             15,128,151  
Payments of Stock Issuance Costs   $ 680,000 $ 171,000 $ 327,000 $ 369,000          
Units Issued, Price per Unit   $ 0.60                
Proceeds from Issuance or Sale of Equity, Total   $ 5,500,000                
Proceeds from Issuance or Sale of Equity, Net   $ 4,820,000                
Proceeds from Issuance of Common Stock, Net     $ 1,213,000 $ 2,368,000 $ 2,092,000   $ 2,368,000 $ 6,629,000 $ 2,092,000  
Cash and Cash Equivalents, at Carrying Value, Ending Balance             3,513,000 2,400,000    
Working Capital               2,261,000    
Retained Earnings (Accumulated Deficit), Ending Balance             $ (187,640,000) $ (227,435,000)    
ThermoGenesis [Member]                    
Noncontrolling Interest, Ownership Percentage by Parent               80.00%    
SynGen [Member]                    
Percentage Of Common Stock Issued To Acquiree Shareholders               20.00%   20.00%
Common Warrants [Member]                    
Class of Warrant or Right, Exercise Price of Warrants or Rights   $ 0.60                
Warrants and Rights Outstanding, Term   5 years                
Warrants Issused in Private Placement [Member]                    
Class of Warrant or Right, Exercise Price of Warrants or Rights     $ 2.68              
Warrants and Rights Outstanding, Term     5 years 182 days              
Class of Warrant or Right, Number of Securities Called by Warrants or Rights     304,818              
Units [Member]                    
Number of Units Issued   6,475,001                
Convertible Units, Number of Common Shares Called by Each Unit   1                
Convertible Units, Number of Common Warrants Called by Each Unit   1                
Units [Member] | Common Warrants [Member]                    
Class of Warrant or Right, Number of Securities Called by Each Warrant or Right   1                
Pre-funded Units [member]                    
Number of Units Issued   2,691,666                
Convertible Units, Number of Common Warrants Called by Each Unit   1                
Convertible Units, Number of Pre-funded Warrants Called by Each Unit   1                
Number of Units Exercised           2,691,666        
Pre-funded Units [member] | Common Warrants [Member]                    
Class of Warrant or Right, Number of Securities Called by Each Warrant or Right   1                
Pre-funded Units [member] | Pre-funded Warrant [Member]                    
Class of Warrant or Right, Number of Securities Called by Each Warrant or Right   1                
Private Placement [Member]                    
Stock Issued During Period, Shares, New Issues 1,000,000                  
Common Stock, Par or Stated Value Per Share $ 0.001                  
Shares Issued, Price Per Share $ 0.18                  
Class of Warrant or Right, Issued During Period 2,965,000                  
Warrants Issued, Price Per Warrant $ 0.17                  
Class of Warrant or Right, Number of Securities Called by Each Warrant or Right 1                  
Class of Warrant or Right, Exercise Price of Warrants or Rights $ 0.01                  
Proceeds from Issuance of Private Placement $ 684,000                  
Proceeds from Issuance of Private Placement, Net 623,000                  
Payments of Stock Issuance Costs $ 61,000                  
Boyalife Investment Fund II, Inc. [Member] | Revolving Credit Facility [Member]                    
Long-term Line of Credit, Total               $ 7,200,000    
Line of Credit Facility, Maximum Borrowing Capacity               $ 10,000,000