Note 4 - Intangible Assets and Goodwill (Tables)

12 Months Ended

Dec. 31, 2018

Notes Tables

Schedule of Intangible Assets and Goodwill [Table Text Block]

	Intangible Assets			Goodwill
Balance at December 31, 2017, net	$	21,629,000		$	13,976,000
Amortization and foreign exchange (current year)		(152,000	)		--
Impairment loss		(19,886,000	)		(13,195,000	)
Balance at December 31, 2018, net	$	1,591,000		$	781,000

Schedule of Finite-Lived Intangible Assets [Table Text Block]

As of December 31, 2018
	Weighted Average Amortization Period (in Years)		Gross Carrying Amount		Accumulated Amortization		Impairment		Net
Trade names		3	$	54,000	$	38,000			$	16,000
Developed technology		10		318,000		48,000				270,000
Licenses		7		448,000		307,000				141,000
Device registration		7		84,000		68,000	$	16,000		--
Customer relationships		3		451,000		430,000		--		21,000
Amortizable intangible assets				1,355,000		891,000		16,000		448,000
In process technology				1,143,000		--		--		1,143,000
Clinical protocols				19,870,000		--		19,870,000		--
Total			$	22,368,000	$	891,000	$	19,886,000	$	1,591,000

As of December 31, 2017
	Weighted Average Amortization Period (in Years)		Gross Carrying Amount		Accumulated Amortization		Net
Trade names		7	$	56,000	$	21,000	$	35,000
Developed technology		10		318,000		16,000		302,000
Licenses		7		489,000		271,000		218,000
Customer relationships		3		490,000		456,000		34,000
Device registration		7		92,000		65,000		27,000
Amortizable intangible assets				1,445,000		829,000		616,000
In process technology				1,143,000		--		1,143,000
Clinical protocols				19,870,000		--		19,870,000
Total			$	22,458,000	$	829,000	$	21,629,000

Schedule of Finite-Lived Intangible Assets, Future Amortization Expense [Table Text Block]

Year Ended December 31,
2019	$	122,000
2020		111,000
2021		40,000
2022		32,000
2023		32,000
Thereafter		111,000
Total	$	448,000