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Note 3 - Acquisition of SynGen Inc. (Tables)
 6 Months Ended
Jun. 30, 2018
Notes Tables  
Business Acquisition, Pro Forma Information [Table Text Block]
   
Three Months Ended
June 30, 2017
    
Six Months Ended
June 30, 2017
  
Net revenues
   $
3,758,000
     $
7,138,000
  
Net loss
   $
(1,712,000
 )   $
(3,960,000
 )
Basic and diluted net loss per common share
   $
(0.17
 )   $
(0.40
 )