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Note 8 - Segment Reporting (Tables)
3 Months Ended
Mar. 31, 2018
Notes Tables  
Reconciliation of Revenue from Segments to Consolidated [Table Text Block]
   
Three Months Ended March 31, 2018
 
   
Clinical
Development
   
Device
   
Total
 
Net revenues
  $
62,000
    $
1,805,000
    $
1,867,000
 
Cost of revenues
   
71,000
     
1,444,000
     
1,515,000
 
Gross profit
   
(9,000
)    
361,000
     
352,000
 
                         
Operating expenses
   
1,179,000
     
2,429,000
     
3,608,000
 
Operating loss
  $
(1,188,000
)   $
(2,068,000
)   $
(3,256,000
)
                         
Depreciation and amortization
  $
68,000
    $
91,000
    $
159,000
 
                         
Stock-based compensation expense
  $
98,000
    $
39,000
    $
137,000
 
Goodwill
  $
13,195,000
    $
781,000
    $
13,976,000
 
Total assets
  $
38,941,000
    $
11,240,000
    $
50,181,000
 
   
Three Months Ended March 31, 2017
 
   
Clinical
Development
   
Device
   
Total
 
Net revenues
  $
153,000
    $
3,099,000
    $
3,252,000
 
Cost of revenues
   
124,000
     
1,751,000
     
1,875,000
 
Gross profit
   
29,000
     
1,348,000
     
1,377,000
 
                         
Operating expenses
   
1,934,000
     
1,559,000
     
3,493,000
 
Operating loss
  $
(1,905,000
)   $
(211,000
)   $
(2,116,000
)
                         
Depreciation and amortization
  $
116,000
    $
69,000
    $
185,000
 
Stock-based compensation expense
  $
151,000
    $
96,000
    $
247,000