Exhibit 21.1

Subsidiaries of Navidea Biopharmaceuticals, Inc.

Subsidiaries	Jurisdiction of Incorporation	Percentage Owned by Registrant
Cardiosonix Ltd.	Israel		100	%
Cira Biosciences, Inc.	Delaware, USA		90	%
RIGSTech I Corporation	Delaware, USA		100	%
Navidea Biopharmaceuticals Limited	United Kingdom		100	%