Note 2 - Summary of Significant Accounting Policies - Summary of Useful Lives of Assets (Details)	12 Months Ended
	Dec. 31, 2017
Minimum [Member] | Office Equipment [Member]
Computer software (in years) (Year)	3 years
Minimum [Member] | Laboratory Equipment [Member]
Computer software (in years) (Year)	5 years
Minimum [Member] | Computer Software, Intangible Asset [Member]
Computer software (in years) (Year)	3 years
Maximum [Member] | Office Equipment [Member]
Computer software (in years) (Year)	7 years
Maximum [Member] | Laboratory Equipment [Member]
Computer software (in years) (Year)	7 years
Maximum [Member] | Computer Software, Intangible Asset [Member]
Computer software (in years) (Year)	5 years