<SEC-DOCUMENT>0000080255-23-002573-index.html : 20230214
<SEC-HEADER>0000080255-23-002573.hdr.sgml : 20230214
<ACCEPTANCE-DATETIME>20230214123808
ACCESSION NUMBER:		0000080255-23-002573
CONFORMED SUBMISSION TYPE:	SC 13G/A
CONFIRMING COPY:	
PUBLIC DOCUMENT COUNT:		1
FILED AS OF DATE:		20230214
DATE AS OF CHANGE:		20230214

SUBJECT COMPANY:	

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			ALNYLAM PHARMACEUTICALS, INC.
		CENTRAL INDEX KEY:			0001178670
		STANDARD INDUSTRIAL CLASSIFICATION:	PHARMACEUTICAL PREPARATIONS [2834]
		IRS NUMBER:				770602661
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		SC 13G/A
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	005-79884

	BUSINESS ADDRESS:	
		STREET 1:		675 WEST KENDALL STREET
		STREET 2:		HENRI A. TERMEER SQUARE
		CITY:			CAMBRIDGE
		STATE:			MA
		ZIP:			02142
		BUSINESS PHONE:		(617) 551-8200

	MAIL ADDRESS:	
		STREET 1:		675 WEST KENDALL STREET
		STREET 2:		HENRI A. TERMEER SQUARE
		CITY:			CAMBRIDGE
		STATE:			MA
		ZIP:			02142

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	ALNYLAM PHARMACEUTICALS INC
		DATE OF NAME CHANGE:	20020724

FILED BY:		

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			PRICE T ROWE ASSOCIATES INC /MD/
		CENTRAL INDEX KEY:			0000080255
		STANDARD INDUSTRIAL CLASSIFICATION:	SECURITY & COMMODITY BROKERS, DEALERS, EXCHANGES & SERVICES [6200]
		IRS NUMBER:				520556948
		STATE OF INCORPORATION:			MD
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		SC 13G/A

	BUSINESS ADDRESS:	
		STREET 1:		100 EAST PRATT ST
		CITY:			BALTIMORE
		STATE:			MD
		ZIP:			21202
		BUSINESS PHONE:		(410)345-2000

	MAIL ADDRESS:	
		STREET 1:		P.O. BOX 89000
		CITY:			BALTIMORE
		STATE:			MD
		ZIP:			21289
</SEC-HEADER>
<DOCUMENT>
<TYPE>SC 13G/A
<SEQUENCE>1
<FILENAME>alny13gadec22.txt
<TEXT>
Document 1 - file: alny13gadec22.txt

</DOCUMENT>
</SEC-DOCUMENT>