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Proc-Type: 2001,MIC-CLEAR
Originator-Name: webmaster@www.sec.gov
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MIC-Info: RSA-MD5,RSA,
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 UXL9ZJNGGHk3MVK6QkuDyg==

<SEC-DOCUMENT>0001326393-06-000002.txt : 20060214
<SEC-HEADER>0001326393-06-000002.hdr.sgml : 20060214
<ACCEPTANCE-DATETIME>20060214180536
ACCESSION NUMBER:		0001326393-06-000002
CONFORMED SUBMISSION TYPE:	5
PUBLIC DOCUMENT COUNT:		1
CONFORMED PERIOD OF REPORT:	20051231
FILED AS OF DATE:		20060214
DATE AS OF CHANGE:		20060214

ISSUER:		

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			OFFICE DEPOT INC
		CENTRAL INDEX KEY:			0000800240
		STANDARD INDUSTRIAL CLASSIFICATION:	RETAIL-MISCELLANEOUS SHOPPING GOODS STORES [5940]
		IRS NUMBER:				592663954
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1226

	BUSINESS ADDRESS:	
		STREET 1:		2200 OLD GERMANTOWN RD
		CITY:			DELRAY BEACH
		STATE:			FL
		ZIP:			33445
		BUSINESS PHONE:		5612664800

	MAIL ADDRESS:	
		STREET 1:		2200 OLD GERMANTOWN ROAD
		STREET 2:		2200 OLD GERMANTOWN ROAD
		CITY:			DELRAY BEACH
		STATE:			FL
		ZIP:			33445

REPORTING-OWNER:	

	OWNER DATA:	
		COMPANY CONFORMED NAME:			Pianin Randy
		CENTRAL INDEX KEY:			0001326393

	FILING VALUES:
		FORM TYPE:		5
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	001-10948
		FILM NUMBER:		06618403

	BUSINESS ADDRESS:	
		BUSINESS PHONE:		561-438-4800

	MAIL ADDRESS:	
		STREET 1:		2200 OLD GERMANTOWN ROAD
		STREET 2:		MAILCODE:  LEGL
		CITY:			DELRAY BEACH
		STATE:			FL
		ZIP:			33445
</SEC-HEADER>
<DOCUMENT>
<TYPE>5
<SEQUENCE>1
<FILENAME>pia165.xml
<TEXT>
<XML>
<?xml version="1.0"?>
<ownershipDocument>

    <schemaVersion>X0202</schemaVersion>

    <documentType>5</documentType>

    <periodOfReport>2005-12-31</periodOfReport>

    <notSubjectToSection16>0</notSubjectToSection16>

    <form3HoldingsReported>1</form3HoldingsReported>

    <form4TransactionsReported>0</form4TransactionsReported>

    <issuer>
        <issuerCik>0000800240</issuerCik>
        <issuerName>OFFICE DEPOT INC</issuerName>
        <issuerTradingSymbol>ODP</issuerTradingSymbol>
    </issuer>

    <reportingOwner>
        <reportingOwnerId>
            <rptOwnerCik>0001326393</rptOwnerCik>
            <rptOwnerName>Pianin Randy</rptOwnerName>
        </reportingOwnerId>
        <reportingOwnerAddress>
            <rptOwnerStreet1>2200 OLD GERMANTOWN ROAD</rptOwnerStreet1>
            <rptOwnerStreet2>MAIL CODE: LEGL</rptOwnerStreet2>
            <rptOwnerCity>DELRAY BEACH</rptOwnerCity>
            <rptOwnerState>FL</rptOwnerState>
            <rptOwnerZipCode>33445</rptOwnerZipCode>
            <rptOwnerStateDescription></rptOwnerStateDescription>
        </reportingOwnerAddress>
        <reportingOwnerRelationship>
            <isDirector>0</isDirector>
            <isOfficer>1</isOfficer>
            <isTenPercentOwner>0</isTenPercentOwner>
            <isOther>0</isOther>
            <officerTitle>SVP-Finance &amp; Controller</officerTitle>
        </reportingOwnerRelationship>
    </reportingOwner>

    <nonDerivativeTable>
        <nonDerivativeHolding>
            <securityTitle>
                <value>Restricted Stock</value>
                <footnoteId id="F1"/>
            </securityTitle>
            <transactionCoding>
                <transactionFormType>3</transactionFormType>
            </transactionCoding>
            <postTransactionAmounts>
                <sharesOwnedFollowingTransaction>
                    <value>13735</value>
                    <footnoteId id="F2"/>
                </sharesOwnedFollowingTransaction>
            </postTransactionAmounts>
            <ownershipNature>
                <directOrIndirectOwnership>
                    <value>D</value>
                </directOrIndirectOwnership>
                <natureOfOwnership>
                    <value></value>
                </natureOfOwnership>
            </ownershipNature>
        </nonDerivativeHolding>
    </nonDerivativeTable>

    <footnotes>
        <footnote id="F1">Restricted stock vests upon attainment of performance targets based upon earnings per share as determined by the Compensation Committee.   Half vests upon attainment of one target, and the remaining half vests upon attainment of a higher target.   If targets are not met within three (3) years, the restricted stock expires unvested.</footnote>
        <footnote id="F2">4000 shares of Restricted Stock was inadvertently omitted from the reporting person's original Form 3, and also were omitted from the Form 4 filed by the reporting person after his original Form 3 was filed.</footnote>
    </footnotes>

    <remarks></remarks>

    <ownerSignature>
        <signatureName>By: Anne Zuckerman, Attorney-in-Fact for:</signatureName>
        <signatureDate>2006-02-14</signatureDate>
    </ownerSignature>
</ownershipDocument>
</XML>
</TEXT>
</DOCUMENT>
</SEC-DOCUMENT>
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