<SEC-DOCUMENT>0001615774-18-003654-index.html : 20180511
<SEC-HEADER>0001615774-18-003654.hdr.sgml : 20180511
<ACCEPTANCE-DATETIME>20180511173148
ACCESSION NUMBER:		0001615774-18-003654
CONFORMED SUBMISSION TYPE:	424B5
PUBLIC DOCUMENT COUNT:		4
FILED AS OF DATE:		20180511
DATE AS OF CHANGE:		20180511

FILER:

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			CYTRX CORP
		CENTRAL INDEX KEY:			0000799698
		STANDARD INDUSTRIAL CLASSIFICATION:	BIOLOGICAL PRODUCTS (NO DIAGNOSTIC SUBSTANCES) [2836]
		IRS NUMBER:				581642750
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		424B5
		SEC ACT:		1933 Act
		SEC FILE NUMBER:	333-217184
		FILM NUMBER:		18828084

	BUSINESS ADDRESS:	
		STREET 1:		11726 SAN VICENTE BOULEVARD
		STREET 2:		SUITE 650
		CITY:			LOS ANGELES
		STATE:			CA
		ZIP:			90049
		BUSINESS PHONE:		310-826-5648

	MAIL ADDRESS:	
		STREET 1:		11726 SAN VICENTE BOULEVARD
		STREET 2:		SUITE 650
		CITY:			LOS ANGELES
		STATE:			CA
		ZIP:			90049
</SEC-HEADER>
<DOCUMENT>
<TYPE>424B5
<SEQUENCE>1
<FILENAME>s110127_424b5.htm
<DESCRIPTION>PROSPECTUS SUPPLEMENT
<TEXT>
Document 1 - file: s110127_424b5.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>2
<FILENAME>img001_v1.jpg
<DESCRIPTION>GRAPHIC
<TEXT>
Document 2 - file: img001_v1.jpg

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>3
<FILENAME>img002_v1.jpg
<DESCRIPTION>GRAPHIC
<TEXT>
Document 3 - file: img002_v1.jpg

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>4
<FILENAME>logo_s3.jpg
<DESCRIPTION>GRAPHIC
<TEXT>
Document 4 - file: logo_s3.jpg

</DOCUMENT>
</SEC-DOCUMENT>