Income Taxes (Details Narrative) - USD ($) $ in Millions	12 Months Ended
	Dec. 31, 2021	Dec. 31, 2020
Operating Loss Carryforwards [Line Items]
Operating loss carryforwards, expiration date	expire in 2024 through 2037
Tax credit expiration date, description	expire in 2022 through 2036
Deferred tax valuation allowance, percentage	100.00%
Deferred tax valuation allowance	$ 1.6	$ 9.5
Domestic Tax Authority [Member]
Operating Loss Carryforwards [Line Items]
Operating loss carryforwards	335.0
Operating loss carryforwards, not subject to limitation	24.4
Tax credit research and development	16.0
Domestic Tax Authority [Member] | Shareholders [Member]
Operating Loss Carryforwards [Line Items]
Operating loss carryforwards	67.6
Domestic Tax Authority [Member] | Expire in 2024 Through 2037 [Member]
Operating Loss Carryforwards [Line Items]
Operating loss carryforwards	310.3
Domestic Tax Authority [Member] | Unrestricted [Member]
Operating Loss Carryforwards [Line Items]
Operating loss carryforwards	267.4
State and Local Jurisdiction [Member]
Operating Loss Carryforwards [Line Items]
Operating loss carryforwards	259.9
Tax credit research and development	22.0
State and Local Jurisdiction [Member] | Unrestricted [Member]
Operating Loss Carryforwards [Line Items]
Operating loss carryforwards	$ 259.9
California [Member]
Operating Loss Carryforwards [Line Items]
Operating loss carryforwards, expiration date	expire in 2029 through 2040.