Stock Based Compensation - Schedule of Total Stock-based Compensation Expense from Stock Options, Restricted Stock and Warrants (Details) - Stock Options, RestrictedStock and Warrants [Member] - USD ($)	3 Months Ended
	Mar. 31, 2019	Mar. 31, 2018
Employees [Member]
Allocated employee and non-employee stock-based compensation expense, Total	$ 213,174	$ 428,989
Non Employees [Member]
Allocated employee and non-employee stock-based compensation expense, Total		21,350
Research and Development Expense [Member] | Employees [Member]
Allocated employee and non-employee stock-based compensation expense, Total
Research and Development Expense [Member] | Non Employees [Member]
Allocated employee and non-employee stock-based compensation expense, Total
General and Administrative Expense [Member] | Employees [Member]
Allocated employee and non-employee stock-based compensation expense, Total	213,174	428,989
General and Administrative Expense [Member] | Non Employees [Member]
Allocated employee and non-employee stock-based compensation expense, Total		$ 21,350