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CONDENSED STATEMENTS OF OPERATIONS (Unaudited) - USD ($)
3 Months Ended 9 Months Ended
Sep. 30, 2017
Sep. 30, 2016
Sep. 30, 2017
Sep. 30, 2016
Revenue:        
License revenue $ 0 $ 0 $ 0 $ 100,000
Expenses:        
Research and development 4,755,191 8,927,037 17,675,079 29,531,609
General and administrative 3,418,808 2,771,732 9,534,872 12,859,069
Total expenses 8,173,999 11,698,769 27,209,951 42,390,678
Loss before other income (loss) (8,173,999) (11,698,769) (27,209,951) (42,290,678)
Other income (loss):        
Interest income 119,900 68,635 271,292 195,809
Interest expense (828,120) (781,038) (2,999,230) (1,939,186)
Other (loss), net (6,055) (10,489) (16,722) (4,398)
Gain (loss) on warrant derivative liabilities 3,763,855 246,211 (572,209) 939,668
Net loss $ (5,124,419) $ (12,175,450) $ (30,526,820) $ (43,098,785)
Basic and diluted net loss per share (in dollars per share) $ (0.19) $ (0.80) $ (1.33) $ (3.45)
Basic and diluted weighted-average shares outstanding (in shares) 26,618,098 15,173,742 22,936,843 12,500,295