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Stock Based Compensation, by Exercise Price Range (Details)
$ / shares in Units, $ in Millions
9 Months Ended
Sep. 30, 2016
USD ($)
$ / shares
shares
Dec. 31, 2015
$ / shares
shares
Stock Options [Member]    
Share based compensation, shares authorized under significant ranges of outstanding stock option plans in period [Abstract]    
Number of Options (in shares) | shares 13,437,822  
Weighted-Average Remaining Contractual Life 7 years 7 months 28 days  
Weighted-Average Exercise Price (in dollars per share) $ 3.04  
Number of Options Exercisable (in shares) | shares 9,842,803  
Weighted-Average Remaining Contractual Life 7 years 2 months 23 days  
Weighted-Average Exercise Price, Options Exercisable (in dollars per share) $ 3.27  
The aggregate intrinsic value of outstanding options | $ $ 0  
Aggregate intrinsic value of options vested | $ $ 0  
Closing price of the common stock (in dollars per share) $ 0.59  
Warrants [Member]    
Share based compensation, shares authorized under significant ranges of outstanding stock option plans in period [Abstract]    
Warrants outstanding (in shares) | shares 30,559,148 7,225,472
Weighted-average exercise price of warrants outstanding (in dollars per share) 0.80 4.28
Range $0.60 - $2.00 [Member] | Stock Options [Member]    
Share based compensation, shares authorized under significant ranges of outstanding stock option plans in period [Abstract]    
Range of Exercise Prices, Lower Range (in dollars per share) $ 0.60  
Range of Exercise Prices, Upper Range (in dollars per share) $ 2.00  
Number of Options (in shares) | shares 1,274,498  
Weighted-Average Remaining Contractual Life 6 years 4 months 2 days  
Weighted-Average Exercise Price (in dollars per share) $ 1.78  
Number of Options Exercisable (in shares) | shares 1,224,498  
Weighted-Average Remaining Contractual Life 6 years 2 months 8 days  
Weighted-Average Exercise Price, Options Exercisable (in dollars per share) $ 1.83  
Range $2.01 - 2.50 [Member] | Stock Options [Member]    
Share based compensation, shares authorized under significant ranges of outstanding stock option plans in period [Abstract]    
Range of Exercise Prices, Lower Range (in dollars per share) 2.01  
Range of Exercise Prices, Upper Range (in dollars per share) $ 2.50  
Number of Options (in shares) | shares 7,899,179  
Weighted-Average Remaining Contractual Life 8 years 4 months 28 days  
Weighted-Average Exercise Price (in dollars per share) $ 2.33  
Number of Options Exercisable (in shares) | shares 4,522,874  
Weighted-Average Remaining Contractual Life 8 years 22 days  
Weighted-Average Exercise Price, Options Exercisable (in dollars per share) $ 2.30  
Range $2.51 - 4.00 [Member] | Stock Options [Member]    
Share based compensation, shares authorized under significant ranges of outstanding stock option plans in period [Abstract]    
Range of Exercise Prices, Lower Range (in dollars per share) 2.51  
Range of Exercise Prices, Upper Range (in dollars per share) $ 4.00  
Number of Options (in shares) | shares 968,291  
Weighted-Average Remaining Contractual Life 7 years 4 months 13 days  
Weighted-Average Exercise Price (in dollars per share) $ 2.88  
Number of Options Exercisable (in shares) | shares 937,458  
Weighted-Average Remaining Contractual Life 7 years 4 months 2 days  
Weighted-Average Exercise Price, Options Exercisable (in dollars per share) $ 2.87  
Range $4.01 - 32.55 [Member] | Stock Options [Member]    
Share based compensation, shares authorized under significant ranges of outstanding stock option plans in period [Abstract]    
Range of Exercise Prices, Lower Range (in dollars per share) 4.01  
Range of Exercise Prices, Upper Range (in dollars per share) $ 32.55  
Number of Options (in shares) | shares 3,295,854  
Weighted-Average Remaining Contractual Life 6 years 5 months 16 days  
Weighted-Average Exercise Price (in dollars per share) $ 5.30  
Number of Options Exercisable (in shares) | shares 3,157,973  
Weighted-Average Remaining Contractual Life 6 years 5 months 1 day  
Weighted-Average Exercise Price, Options Exercisable (in dollars per share) $ 5.32