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STATEMENTS OF STOCKHOLDERS' EQUITY - USD ($)
Common Stock [Member]
Additional Paid-in Capital [Member]
Accumulated Deficit [Member]
Treasury Stock [Member]
Total
Balance at Dec. 31, 2012 $ 30,608 $ 261,318,638 $ (228,904,167) $ (2,279,238) $ 30,165,841
Balance (in shares) at Dec. 31, 2012 30,607,916        
Increase (Decrease) in Stockholders' Equity [Roll Forward]          
Issuance of stock options/warrants for compensation and services $ 0 3,798,717 0 0 3,798,717
Issuance of stock options/warrants for compensation and services (in shares) 0        
Common stock issued in connection with a public offering $ 11,500 24,083,030 0 0 24,094,530
Common stock issued in connection with a public offering (in shares) 11,500,000        
Restricted stock expense $ 0 186,389 0 0 186,389
Options and warrants exercised $ 10 39,326 0 0 39,336
Options and warrants exercised (in shares) 9,048        
Repurchase of common stock for treasury $ 0 0 0 (138,009) (138,009)
Net loss 0 0 (47,485,437) 0 (47,485,437)
Balance at Dec. 31, 2013 $ 42,118 289,426,100 (276,389,604) (2,417,247) 10,661,367
Balance (in shares) at Dec. 31, 2013 42,116,964        
Increase (Decrease) in Stockholders' Equity [Roll Forward]          
Issuance of stock options/warrants for compensation and services $ 0 5,139,348 0 0 5,139,348
Issuance of stock options/warrants for compensation and services (in shares) 0        
Common stock issued in connection with a public offering $ 13,225 80,522,176 0 0 80,535,401
Common stock issued in connection with a public offering (in shares) 13,225,000        
Restricted stock expense         626,900
Options and warrants exercised $ 281 431,660 0 0 431,941
Options and warrants exercised (in shares) 280,022        
Issuance of restricted stock for compensation $ 100 626,900 0 0 627,000
Issuance of restricted stock for compensation (in shares) 100,000        
Issuance of common stock for compensation $ 200 829,800 0 0 830,000
Issuance of common stock for compensation (in shares) 200,000        
Repurchase of common stock for treasury $ 0 0 0 (195,614) (195,614)
Net loss 0 0 (30,117,980) 0 (30,117,980)
Balance at Dec. 31, 2014 $ 55,924 376,975,984 (306,507,584) (2,612,861) $ 67,911,463
Balance (in shares) at Dec. 31, 2014 55,921,986       55,921,986
Increase (Decrease) in Stockholders' Equity [Roll Forward]          
Issuance of stock options/warrants for compensation and services $ 0 7,384,656 0 0 $ 7,384,656
Issuance of stock options/warrants for compensation and services (in shares) 0        
Common stock issued in connection with a public offering $ 10,465 26,769,603 0 0 26,780,068
Common stock issued in connection with a public offering (in shares) 10,465,000        
Restricted stock expense         0
Options and warrants exercised $ 290 589,711 0 0 590,001
Options and warrants exercised (in shares) 292,354        
Retirement of treasury stock $ (199) (2,612,662) 0 2,612,861 0
Retirement of treasury stock (in shares) (199,275)        
Net loss $ 0 0 (58,587,190) 0 (58,587,190)
Balance at Dec. 31, 2015 $ 66,480 $ 409,107,292 $ (365,094,774) $ 0 $ 44,078,998
Balance (in shares) at Dec. 31, 2015 66,480,065       66,480,065