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CONSOLIDATED STATEMENTS OF CASH FLOWS (USD $)
12 Months Ended
Dec. 31, 2013
Dec. 31, 2012
Dec. 31, 2011
Cash flows from operating activities:      
Net loss $ (47,485,437) $ (17,963,873) $ (14,424,545)
Adjustments to reconcile net loss to net cash used in operating activities:      
Depreciation and amortization 120,399 113,936 95,517
Loss on retirement of equipment and furnishings 2,595 42,267 10,206
Gain (loss) on warrant liability 20,210,094 (2,766,704) (7,915,027)
Foreign exchange (gain) loss (118,438) 0 17,834
Stock-based compensation expense 3,985,106 2,391,529 1,436,840
Changes in assets and liabilities:      
Receivable (835) 65,902 83,302
Interest receivable 18,053 14,758 76,349
Income taxes recoverable 0 0 519,158
Prepaid expenses and other current assets (1,132,428) (173,245) 277,232
Accounts payable 789,655 984,547 1,046,539
Accrued expenses and other current liabilities (139,747) (1,753,767) 2,105,212
Total adjustments 23,734,454 (1,080,777) (2,246,838)
Net cash used in operating activities (23,750,983) (19,044,650) (16,671,383)
Cash flows from investing activities:      
Proceeds from matured marketable securities 24,000,000 23,125,442 25,644,481
Purchase of short-term investments (27,084,980) (29,067,770) (23,134,292)
Proceeds from sale of affiliate's shares 0 0 6,938,603
Purchases of equipment and furnishings (41,809) (141,639) (52,868)
Net cash provided by (used in) investing activities (3,126,789) (6,083,967) 9,395,924
Cash flows from financing activities:      
Proceeds from common stock issued in public offering, net of fees 24,094,530 21,476,815 18,939,619
Proceeds from issuance of restricted stock to employee 0 100 0
Repurchase of Company's own stock for treasury (117,070) 0 0
Net proceeds from exercise of stock options and warrants 39,336 7,200 0
Net cash provided by financing activities 24,016,796 21,484,115 18,939,619
Net increase (decrease) in cash and cash equivalents (2,860,976) (3,644,502) 11,664,160
Cash and cash equivalents at beginning of year 14,344,088 17,988,590 6,324,430
Cash and cash equivalents at end of year 11,483,112 14,344,088 17,988,590
Supplemental disclosures of non-cash financing activities:      
Warrants issued in connection with financing 0 0 12,216,680
Repurchase of Company's own stock for treasury 27,829 0 0
Equipment and furnishings purchased but not paid 3,360 1,506 0
Supplemental disclosure of Cash Flow Information:      
Cash paid during the year for income taxes $ 25,750 $ 0 $ 0