Stockholders' Equity/(Deficit) (Tables)

12 Months Ended

Dec. 31, 2016

Equity [Abstract]

Summary of Preferred Stock Allocated to Investors

The Purchase Agreement provides for the Company to issue and sell to the Investor shares of the Company’s preferred stock in the amounts set forth in the following table (numbers have been adjusted for the February 2016 reverse stock split):

Convertible Preferred Stock	Shares		Price Per Share		Total Investment
Series AA-1		8,427,004	$	12.00	$	101,124,048
Series AA-2		7,223,145	$	6.00		43,338,870
		15,650,149			$	144,462,918

Stock Options Valuation Assumptions

The assumptions used in the Black-Scholes model were as follows for stock options granted in the years ended December 31, 2016, 2015 and 2014:

	2016	2015	2014
Risk-free interest rate	1.29 - 2.25%	1.78 - 2.00%	2.10 - 2.70%
Expected volatility of common stock	80.87 - 82.69%	64.47 - 65.95%	63.5 - 65.0%
Dividend yield	0%	0%	0%
Expected life of options	8.2 years	6.1 - 8.2 years	6.1 - 8.2 years

Summary of Stock Option Activity

Additional information with respect to both plans stock option activity is as follows:

	Number of Shares			Weighted Average Exercise Price
Outstanding at December 31, 2013		249,656		$	39.72
Granted		85,524		$	25.68
Exercised		—		$	—
Cancelled		(27,390	)	$	41.76
Outstanding at December 31, 2014		307,791		$	32.04
Granted		137,667		$	12.48
Exercised		—		$	—
Cancelled		(70,174	)	$	32.88
Outstanding at December 31, 2015		375,283		$	32.04
Granted		22,493		$	2.74
Exercised		—		$	—
Cancelled		(65,361	)	$	32.82
Outstanding at December 31, 2016		332,415		$	21.55
Options exercisable at December 31, 2014		221,109		$	33.24
Options exercisable at December 31, 2015		275,735		$	27.48
Options exercisable at December 31, 2016		300,751		$	22.30

Stock Options Outstanding

The following table summarizes information about stock options outstanding at December 31, 2016:

Stock Options Outstanding

Range of Exercise Prices	Number of Shares Outstanding		Weighted Average Remaining Contractual Life in Years		Weighted Average Exercise Price
$2.02 - $12.84		164,326		8.23	$	11.16
$26.40 - $26.40		75,158		7.00	$	26.40
$34.68 - $39.00		82,098		1.07	$	35.12
$41.16 - $46.80		10,833		0.92	$	42.67
		332,415		5.94	$	21.55

Estimated Fair Value of Restricted Stock Award

A summary of the status of the restricted stock awards as of December 31, 2016 and changes during the year ended December 31, 2016 is presented as follows:

	Number of Shares			Weighted Average Grant Date Fair Value
Unvested at December 31, 2015		92,696		$	13.20
Granted		388,573		$	3.54
Vested		(209,183	)	$	5.43
Cancelled		(33,165	)	$	4.65
Unvested at December 31, 2016		238,921		$	5.41

Summary of Common Stock Warrants Outstanding

The following table summarizes our common stock warrants outstanding at December 31, 2016:

Common Stock Warrants		Exercise Price		Termination Date
	120,000	$	3.52		10/01/2021