BIORELEASE CORP.
                          340 Granite Street Suite 200
                              Manchester, NH 03102
                        (603) 641-8443 (603) 641-9535 fx

                                 June 15th, 2001

                                    VIA EDGAR

                       Securities and Exchange Commission
                          Division of Corporate Finance
                             450 Fifth Street, N.W.
                              Washington, DC 20549

                              RE: BIORELEASE CORP.

                                 CIK: 0000797662

                         COMMISSION FILE NO. 333-94799;
                           APPLICATION FOR WITHDRAWAL
Ladies and Gentlemen:

Pursuant  to Rule  477(a)  promulgated  under  the  Securities  Act of 1933,  as
amended,  Biorelease  Corp.  (the  "Registrant")  hereby  applies  for an  order
granting the immediate  withdrawal of its  registration  statements on Form S-4,
together  with  all  exhibits  thereto,   Commission  File  No.  333-94799  (the
"Registration Statements"). The Registration Statement was originally filed with
the Securities and Exchange Commission (the "Commission") on January 8, 2000.

The  Registration  Statement  was  filed in  connection  with  the  Registrant's
proposed  acquisition  of Polar  Molecular  Corporation  ("PMC").  That proposed
acquisition has been terminated,  and therefore the Registration Statement is to
be withdrawn.

Accordingly,  that Registrant  requests that an order granting the withdrawal of
the Registration Statement be issued by the Commission as soon as possible.

If you have any questions  regarding the foregoing  application  for withdrawal,
please contact R. Bruce Reeves, CEO of the Registrant, at (603) 641-8443.


Sincerely,
Biorelease Corp.

/s/ R. Bruce Reeves
R. Bruce Reeves, CEO