SECURITIES AND EXCHANGE COMMISSION
                             WASHINGTON, D.C. 20549

                              SEC FILE No.: 0-15260
                                    CUSIP No.

                                   FORM 12b-25
                           Notification of Late Filing
                                  (Check One):
                   [X] Form 10-KSB [ ] Form 11-K [ ] Form 20-F
                         [ ] Form 10-QSB [ ] Form N-SAR

For Period ended:

[x]      Transition Report on Form 10-K
[ ]      Transition Report on Form 10-K
[ ]      Transition Report on Form 10-K
[ ]      Transition Report on Form 10-K
[ ]      Transition Report on Form 10-K
For the Transition Period Ended:_______________________________________________
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Nothing  in this  Form  shall be  construed  to imply  that the  Commission  has
verified any information contained herein.

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If the Notification  relates to a portion of the filing checked above,  identify
the Item(s) to which the notification relates:

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Part I-Registrant Information

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                                 Biorelease Corp
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                            Full Name of Registrant:

                                       N/A
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                           Former Name if Applicable:

                          340 Granite Street, Suite 200
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            Address of Principal Executive Office (Street and Number)

                            Manchester, NH 03102-4004
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                            City, State and Zip Code





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PART II - RULES 12b-25 (b) AND (c)
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If the subject report could not be filed without  unreasonable effort or expense
and the registrant seeks relief pursuant to Rule 12b-25(b), the following should
be completed (Check box if appropriate)

[X]  (a)  The reasons described in reasonable detail in Part III of this form
          could not be eliminated without unreasonable effort or expense;

[ ]  (b)  The subject quarterly report on Form 10-Q will be filed
          on or before the fifth calendar day following the prescribed due date;
          and

[ ]  (c)  The accountant's statement or other exhibit required by
          Rule 12(b)-25(c) has been attached if applicable.

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PART III - NARRATIVE
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State below in reasonable detail the reasons why the Form 10-K, 11-K, 20-K, 10-Q
or N-SAR or a portion  thereof  could not be filed  within the  prescribed  time
period.

The Company's  auditors need more time to finalize the year end audit and insure
that  all SEC  compliance  issues  are  adhered  to in  their  reporting  on the
consolidated financial statements of Biorelease Corp. Additionally the Company's
audit firm has moved recently and has limited resources to finalize at this time
to  complete  their  audit  without   contracting   outside   consultants  at  a
considerable increase in the fee.

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Part IV-Other Information

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Name and telephone number of person to contact in regard to this notification.
R. Bruce Reeves                     (603) 641-8443
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(Name)            `                 (Area code) Telephone Number

Have all other  periodic  reports  required  under section 30 of the  Securities
Exchange Act of 1934 or section 30 of Investment  Company Act of 1940 during the
proceeding 12 months or for such shorter period that the registrant was required
to file such report(s) been filed? If the answer is no, identify report (s).

         [X] Yes           [ ] No

Is it anticipated that any significant  change in results of operations from the
corresponding  period for the last fiscal year will be reflected by the earnings
statements to be included in the subject report or portion thereof?

         [x] Yes           [ ] No

If so: attach an  explanation of the  anticipated  change both  narratively  and
quantitatively, and, if appropriate, state the reasons why a reasonable estimate
of the results cannot be made.

The Company's statement of operations will show a reduced profit over last year.
In  the  prior   year's   financial   statements   approximately   $322,000   of
non-reoccurring  income  on  settlements  of  liabilities  was  included  in the
statement of operations. Such non-reoccurring income will be approximately $1500
for this current year.




Biorelease  Corp has caused this  notification to be signed on its behalf by the
undersigned thereunto duly authorized.

Date     September 27, 2000           By    /s/ R. Bruce Reeves
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                                            R. Bruce Reeves, President


Instruction: The form may be signed by an executive officer of the registrant or
by any other duly  authorized  representative.  The name and title of the person
signing  the form  shall  be typed or  printed  beneath  the  signature.  If the
statement is signed on behalf of the registrant by an authorized  representative
(other than an executive officer), evidence of the representative's authority to
sign on behalf of the registrant shall be filed with the form.

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INTENTIONAL MISTATEMENTS OR OMISSIONS OF FACT CONSTITUTE FEDRAL CRIMINAL
VIOLATIONS (SEE 18 U. S. C. 1001).
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