-----BEGIN PRIVACY-ENHANCED MESSAGE-----
Proc-Type: 2001,MIC-CLEAR
Originator-Name: webmaster@www.sec.gov
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MIC-Info: RSA-MD5,RSA,
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 qkGguQOKxz6k7ZsT0mQv3w==

<SEC-DOCUMENT>0000892251-05-000870.txt : 20051115
<SEC-HEADER>0000892251-05-000870.hdr.sgml : 20051115
<ACCEPTANCE-DATETIME>20051115165941
ACCESSION NUMBER:		0000892251-05-000870
CONFORMED SUBMISSION TYPE:	4
PUBLIC DOCUMENT COUNT:		1
CONFORMED PERIOD OF REPORT:	20051110
FILED AS OF DATE:		20051115
DATE AS OF CHANGE:		20051115

ISSUER:		

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			MERIDIAN BIOSCIENCE INC
		CENTRAL INDEX KEY:			0000794172
		STANDARD INDUSTRIAL CLASSIFICATION:	IN VITRO & IN VIVO DIAGNOSTIC SUBSTANCES [2835]
		IRS NUMBER:				310888197
		STATE OF INCORPORATION:			OH
		FISCAL YEAR END:			0930

	BUSINESS ADDRESS:	
		STREET 1:		3471 RIVER HILLS DR
		CITY:			CINCINNATI
		STATE:			OH
		ZIP:			45244
		BUSINESS PHONE:		5132713700

	MAIL ADDRESS:	
		STREET 1:		3471 RIVER HILLS DRIVE
		CITY:			CINCINNATI
		STATE:			OH
		ZIP:			45244

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	MERIDIAN DIAGNOSTICS INC
		DATE OF NAME CHANGE:	19920703

REPORTING-OWNER:	

	OWNER DATA:	
		COMPANY CONFORMED NAME:			MOTTO WILLIAM J
		CENTRAL INDEX KEY:			0000940435

	FILING VALUES:
		FORM TYPE:		4
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	000-14902
		FILM NUMBER:		051207301

	BUSINESS ADDRESS:	
		STREET 1:		MERIDIAN DIAGNOSTICS INC
		STREET 2:		3471 RIVER HILLS DRIVE
		CITY:			CINCINNATI
		STATE:			OH
		ZIP:			45244
		BUSINESS PHONE:		5132713700

	MAIL ADDRESS:	
		STREET 1:		MERIDIAN BIOSCIENCE INC
		STREET 2:		3471 RIVER HILLS DRIVE
		CITY:			CINCINNATI
		STATE:			OH
		ZIP:			45244
</SEC-HEADER>
<DOCUMENT>
<TYPE>4
<SEQUENCE>1
<FILENAME>motto4111005_ex.xml
<TEXT>
<XML>
<?xml version="1.0"?>
<ownershipDocument>

    <schemaVersion>X0202</schemaVersion>

    <documentType>4</documentType>

    <periodOfReport>2005-11-10</periodOfReport>

    <notSubjectToSection16>0</notSubjectToSection16>

    <issuer>
        <issuerCik>0000794172</issuerCik>
        <issuerName>MERIDIAN BIOSCIENCE INC</issuerName>
        <issuerTradingSymbol>VIVO</issuerTradingSymbol>
    </issuer>

    <reportingOwner>
        <reportingOwnerId>
            <rptOwnerCik>0000940435</rptOwnerCik>
            <rptOwnerName>MOTTO WILLIAM J</rptOwnerName>
        </reportingOwnerId>
        <reportingOwnerAddress>
            <rptOwnerStreet1>MERIDIAN BIOSCIENCE, INC</rptOwnerStreet1>
            <rptOwnerStreet2>3471 RIVER HILLS DRIVE</rptOwnerStreet2>
            <rptOwnerCity>CINCINNATI</rptOwnerCity>
            <rptOwnerState>OH</rptOwnerState>
            <rptOwnerZipCode>45244</rptOwnerZipCode>
            <rptOwnerStateDescription></rptOwnerStateDescription>
        </reportingOwnerAddress>
        <reportingOwnerRelationship>
            <isDirector>1</isDirector>
            <isOfficer>1</isOfficer>
            <isTenPercentOwner>1</isTenPercentOwner>
            <isOther>0</isOther>
            <officerTitle>Chairman, CEO</officerTitle>
        </reportingOwnerRelationship>
    </reportingOwner>

    <nonDerivativeTable>
        <nonDerivativeTransaction>
            <securityTitle>
                <value>Common Stock</value>
            </securityTitle>
            <transactionDate>
                <value>2005-11-14</value>
            </transactionDate>
            <transactionCoding>
                <transactionFormType>4</transactionFormType>
                <transactionCode>M</transactionCode>
                <equitySwapInvolved>0</equitySwapInvolved>
            </transactionCoding>
            <transactionAmounts>
                <transactionShares>
                    <value>30000</value>
                </transactionShares>
                <transactionPricePerShare>
                    <value>4.79</value>
                </transactionPricePerShare>
                <transactionAcquiredDisposedCode>
                    <value>A</value>
                </transactionAcquiredDisposedCode>
            </transactionAmounts>
            <postTransactionAmounts>
                <sharesOwnedFollowingTransaction>
                    <value>592500</value>
                </sharesOwnedFollowingTransaction>
            </postTransactionAmounts>
            <ownershipNature>
                <directOrIndirectOwnership>
                    <value>D</value>
                </directOrIndirectOwnership>
            </ownershipNature>
        </nonDerivativeTransaction>
        <nonDerivativeHolding>
            <securityTitle>
                <value>Common Stock</value>
            </securityTitle>
            <postTransactionAmounts>
                <sharesOwnedFollowingTransaction>
                    <value>444750</value>
                </sharesOwnedFollowingTransaction>
            </postTransactionAmounts>
            <ownershipNature>
                <directOrIndirectOwnership>
                    <value>I</value>
                </directOrIndirectOwnership>
                <natureOfOwnership>
                    <value>By Trusts</value>
                    <footnoteId id="F2"/>
                </natureOfOwnership>
            </ownershipNature>
        </nonDerivativeHolding>
        <nonDerivativeHolding>
            <securityTitle>
                <value>Common Stock</value>
            </securityTitle>
            <postTransactionAmounts>
                <sharesOwnedFollowingTransaction>
                    <value>2368156</value>
                </sharesOwnedFollowingTransaction>
            </postTransactionAmounts>
            <ownershipNature>
                <directOrIndirectOwnership>
                    <value>I</value>
                </directOrIndirectOwnership>
                <natureOfOwnership>
                    <value>By partnership</value>
                    <footnoteId id="F1"/>
                </natureOfOwnership>
            </ownershipNature>
        </nonDerivativeHolding>
    </nonDerivativeTable>

    <derivativeTable>
        <derivativeTransaction>
            <securityTitle>
                <value>Option to Buy (Right to Buy Common Stock)</value>
            </securityTitle>
            <conversionOrExercisePrice>
                <value>21.01</value>
            </conversionOrExercisePrice>
            <transactionDate>
                <value>2005-11-10</value>
            </transactionDate>
            <transactionCoding>
                <transactionFormType>4</transactionFormType>
                <transactionCode>A</transactionCode>
                <equitySwapInvolved>0</equitySwapInvolved>
            </transactionCoding>
            <transactionAmounts>
                <transactionShares>
                    <value>10500</value>
                </transactionShares>
                <transactionPricePerShare>
                    <value>0</value>
                </transactionPricePerShare>
                <transactionAcquiredDisposedCode>
                    <value>A</value>
                </transactionAcquiredDisposedCode>
            </transactionAmounts>
            <exerciseDate>
                <footnoteId id="F3"/>
            </exerciseDate>
            <expirationDate>
                <value>2015-11-10</value>
            </expirationDate>
            <underlyingSecurity>
                <underlyingSecurityTitle>
                    <value>Common Stock</value>
                </underlyingSecurityTitle>
                <underlyingSecurityShares>
                    <value>10500</value>
                </underlyingSecurityShares>
            </underlyingSecurity>
            <postTransactionAmounts>
                <sharesOwnedFollowingTransaction>
                    <value>10500</value>
                </sharesOwnedFollowingTransaction>
            </postTransactionAmounts>
            <ownershipNature>
                <directOrIndirectOwnership>
                    <value>D</value>
                </directOrIndirectOwnership>
            </ownershipNature>
        </derivativeTransaction>
        <derivativeTransaction>
            <securityTitle>
                <value>Option to Buy (Right to Buy Common Stock)</value>
            </securityTitle>
            <conversionOrExercisePrice>
                <value>4.79</value>
            </conversionOrExercisePrice>
            <transactionDate>
                <value>2005-11-14</value>
            </transactionDate>
            <transactionCoding>
                <transactionFormType>4</transactionFormType>
                <transactionCode>M</transactionCode>
                <equitySwapInvolved>0</equitySwapInvolved>
            </transactionCoding>
            <transactionAmounts>
                <transactionShares>
                    <value>30000</value>
                </transactionShares>
                <transactionPricePerShare>
                    <value>0</value>
                </transactionPricePerShare>
                <transactionAcquiredDisposedCode>
                    <value>D</value>
                </transactionAcquiredDisposedCode>
            </transactionAmounts>
            <exerciseDate>
                <value>2000-11-16</value>
            </exerciseDate>
            <expirationDate>
                <value>2005-11-12</value>
            </expirationDate>
            <underlyingSecurity>
                <underlyingSecurityTitle>
                    <value>Common Stock</value>
                </underlyingSecurityTitle>
                <underlyingSecurityShares>
                    <value>10500</value>
                </underlyingSecurityShares>
            </underlyingSecurity>
            <postTransactionAmounts>
                <sharesOwnedFollowingTransaction>
                    <value>10500</value>
                </sharesOwnedFollowingTransaction>
            </postTransactionAmounts>
            <ownershipNature>
                <directOrIndirectOwnership>
                    <value>D</value>
                </directOrIndirectOwnership>
            </ownershipNature>
        </derivativeTransaction>
    </derivativeTable>

    <footnotes>
        <footnote id="F1">The sole general partner of this limited partnership, Motto Vivo Family Limited Partnership, is Motto Management, LLC,
which holds 1% of the Limited Partnership. (The 100% owner of Motto Management, LLC is William J. Motto and David H. Motto,
Trustees under the William J. Motto Revocable Trust.) The only other limited partner is William J. Motto and David H. Motto,
Trustees under the William J. Motto Revocable Trust. Mr. Motto disclaims beneficial ownership of Meridian's common stock held
by the Limited Partnership except to the extent of his pecuniary interest therein.</footnote>
        <footnote id="F2">Shares held by irrevocable trusts over which Mr. Motto maintains beneficial ownership.</footnote>
        <footnote id="F3">These non-qualified stock options are granted under the Company's 2004 Equity Compensation Plan and will vest over a three
year period commencing at such time as the Company has reported to the public net earnings of $16,950,000 or greater for
fiscal 2006. If net earnings do not reach $16,950,000 or higher for such year, the options become void.</footnote>
    </footnotes>

    <ownerSignature>
        <signatureName>Melissa Lueke, Attorney-in-Fact for William J. Motto</signatureName>
        <signatureDate>2005-11-15</signatureDate>
    </ownerSignature>
</ownershipDocument>
</XML>
</TEXT>
</DOCUMENT>
</SEC-DOCUMENT>
-----END PRIVACY-ENHANCED MESSAGE-----