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Proc-Type: 2001,MIC-CLEAR
Originator-Name: webmaster@www.sec.gov
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MIC-Info: RSA-MD5,RSA,
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<SEC-DOCUMENT>0000892251-05-000857.txt : 20051115
<SEC-HEADER>0000892251-05-000857.hdr.sgml : 20051115
<ACCEPTANCE-DATETIME>20051115150910
ACCESSION NUMBER:		0000892251-05-000857
CONFORMED SUBMISSION TYPE:	4
PUBLIC DOCUMENT COUNT:		1
CONFORMED PERIOD OF REPORT:	20051110
FILED AS OF DATE:		20051115
DATE AS OF CHANGE:		20051115

REPORTING-OWNER:	

	OWNER DATA:	
		COMPANY CONFORMED NAME:			INTERNO ANTONIO
		CENTRAL INDEX KEY:			0001224659

	FILING VALUES:
		FORM TYPE:		4
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	000-14902
		FILM NUMBER:		051206272

	MAIL ADDRESS:	
		STREET 1:		3471 RIVER HILLS DRIVE
		CITY:			CINCINNATI
		STATE:			OH
		ZIP:			45244

ISSUER:		

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			MERIDIAN BIOSCIENCE INC
		CENTRAL INDEX KEY:			0000794172
		STANDARD INDUSTRIAL CLASSIFICATION:	IN VITRO & IN VIVO DIAGNOSTIC SUBSTANCES [2835]
		IRS NUMBER:				310888197
		STATE OF INCORPORATION:			OH
		FISCAL YEAR END:			0930

	BUSINESS ADDRESS:	
		STREET 1:		3471 RIVER HILLS DR
		CITY:			CINCINNATI
		STATE:			OH
		ZIP:			45244
		BUSINESS PHONE:		5132713700

	MAIL ADDRESS:	
		STREET 1:		3471 RIVER HILLS DRIVE
		CITY:			CINCINNATI
		STATE:			OH
		ZIP:			45244

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	MERIDIAN DIAGNOSTICS INC
		DATE OF NAME CHANGE:	19920703
</SEC-HEADER>
<DOCUMENT>
<TYPE>4
<SEQUENCE>1
<FILENAME>interno4111005_ex.xml
<TEXT>
<XML>
<?xml version="1.0"?>
<ownershipDocument>

    <schemaVersion>X0202</schemaVersion>

    <documentType>4</documentType>

    <periodOfReport>2005-11-10</periodOfReport>

    <notSubjectToSection16>0</notSubjectToSection16>

    <issuer>
        <issuerCik>0000794172</issuerCik>
        <issuerName>MERIDIAN BIOSCIENCE INC</issuerName>
        <issuerTradingSymbol>VIVO</issuerTradingSymbol>
    </issuer>

    <reportingOwner>
        <reportingOwnerId>
            <rptOwnerCik>0001224659</rptOwnerCik>
            <rptOwnerName>INTERNO ANTONIO</rptOwnerName>
        </reportingOwnerId>
        <reportingOwnerAddress>
            <rptOwnerStreet1>3471 RIVER HILLS DRIVE</rptOwnerStreet1>
            <rptOwnerStreet2></rptOwnerStreet2>
            <rptOwnerCity>CINCINNATI</rptOwnerCity>
            <rptOwnerState>OH</rptOwnerState>
            <rptOwnerZipCode>45244</rptOwnerZipCode>
            <rptOwnerStateDescription></rptOwnerStateDescription>
        </reportingOwnerAddress>
        <reportingOwnerRelationship>
            <isDirector>0</isDirector>
            <isOfficer>1</isOfficer>
            <isTenPercentOwner>0</isTenPercentOwner>
            <isOther>0</isOther>
            <officerTitle>President &amp; Man. Dir. of MBE</officerTitle>
        </reportingOwnerRelationship>
    </reportingOwner>

    <nonDerivativeTable>
        <nonDerivativeHolding>
            <securityTitle>
                <value>Common Stock</value>
            </securityTitle>
            <postTransactionAmounts>
                <sharesOwnedFollowingTransaction>
                    <value>243915</value>
                    <footnoteId id="F1"/>
                </sharesOwnedFollowingTransaction>
            </postTransactionAmounts>
            <ownershipNature>
                <directOrIndirectOwnership>
                    <value>D</value>
                </directOrIndirectOwnership>
            </ownershipNature>
        </nonDerivativeHolding>
    </nonDerivativeTable>

    <derivativeTable>
        <derivativeTransaction>
            <securityTitle>
                <value>Option to Buy (Right to Buy Common Stock)</value>
            </securityTitle>
            <conversionOrExercisePrice>
                <value>21.01</value>
            </conversionOrExercisePrice>
            <transactionDate>
                <value>2005-11-10</value>
            </transactionDate>
            <transactionCoding>
                <transactionFormType>4</transactionFormType>
                <transactionCode>A</transactionCode>
                <equitySwapInvolved>0</equitySwapInvolved>
            </transactionCoding>
            <transactionAmounts>
                <transactionShares>
                    <value>10500</value>
                </transactionShares>
                <transactionPricePerShare>
                    <value>0</value>
                </transactionPricePerShare>
                <transactionAcquiredDisposedCode>
                    <value>A</value>
                </transactionAcquiredDisposedCode>
            </transactionAmounts>
            <exerciseDate>
                <footnoteId id="F2"/>
            </exerciseDate>
            <expirationDate>
                <value>2015-11-10</value>
            </expirationDate>
            <underlyingSecurity>
                <underlyingSecurityTitle>
                    <value>Common Stock</value>
                </underlyingSecurityTitle>
                <underlyingSecurityShares>
                    <value>10500</value>
                </underlyingSecurityShares>
            </underlyingSecurity>
            <postTransactionAmounts>
                <sharesOwnedFollowingTransaction>
                    <value>10500</value>
                </sharesOwnedFollowingTransaction>
            </postTransactionAmounts>
            <ownershipNature>
                <directOrIndirectOwnership>
                    <value>D</value>
                </directOrIndirectOwnership>
            </ownershipNature>
        </derivativeTransaction>
    </derivativeTable>

    <footnotes>
        <footnote id="F1">Adjusted to reflect a 3-for-2 stock split by the Company effective September 2, 2005.</footnote>
        <footnote id="F2">These non-qualified stock options are granted under the Company's 2004 Equity Compensation Plan and will vest over a three
year period commencing at such time as the Company has reported to the public net earnings of $16,950,000 or greater for
fiscal 2006. If net earnings do not reach $16,950,000 or higher for such year, the options become void.</footnote>
    </footnotes>

    <ownerSignature>
        <signatureName>Melissa Lueke, as Attorney-in-Fact for Antonio Interno</signatureName>
        <signatureDate>2005-11-15</signatureDate>
    </ownerSignature>
</ownershipDocument>
</XML>
</TEXT>
</DOCUMENT>
</SEC-DOCUMENT>
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