UNITED STATES
                       SECURITIES AND EXCHANGE COMMISSION
                             Washington, D.C. 20549

                                   FORM 12b-25

                                                 Commission File Number 1-14068

                           NOTIFICATION OF LATE FILING

(Check one) [X] Form 10-K and Form 10-KSB [  ] Form 20-F  [  ] Form 11-K
[ ] Form 10-Q and Form 10-QSB Form  [  ] N-SAR

                       For Period Ended DECEMBER 31, 2000
                  [X]Transition Report on Form 10-K and Form 10-KSB
                  __ Transition Report on Form  20-F
                  __ Transition Report on Form 11-K
                  __ Transition Report on Form 10-Q and Form 10-QSB
                  __ Transition Report on Form N-SAR
                  For the Transition Period Ended:

             Read Instructions (on back page) Before Preparing Form.
                              Please Print or Type.

     Nothing in this form shall be construed to imply that the Commission has
verified any information contained herein.

     If the notification relates to a portion of the filing checked above,
identify the item(s) to which the notification relates:________________________
_______________________________________________________________________________

PART I--REGISTRANT INFORMATION

Full Name of Registrant:  SEPRAGEN CORPORATION
                         -------------------------------------------------------

Former Name of Registrant:
                          ------------------------------------------------------

Address of Principal Executive Office (Street and Number):

14500 Doolittle Drive, San Leandro, CA 94577
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PART II--RULES 12B-25(B) AND (C)

If the subject report could not be filed without unreasonable effort or expense
and the registrant seeks relief pursuant to Rule 12b-25b, the following should
be completed. (Check box if appropriate):

[X] (a) The reasons described in reasonable detail in Part III of this form
could not be eliminated without unreasonable effort or expense;
[X] (b) The subject annual report, semi-annual report, transition report on
Forms 10-K, 10-KSB, Form 20-F, 11-K, Form N-SAR, or portion thereof, will be
filed on or before the fifteenth calendar day following the prescribed due date;
or the subject quarterly report or transition report on Forms 10-Q, 10-QSB, or
portion thereof will be filed on or before the fifth calendar day following the
prescribed due date; and
[ ] (c) The accountant's statement or other exhibit required by Rule 12b-25(c)
has been attached if applicable.

PART III--NARRATIVE

State below in reasonable detail the reasons why the Forms 10-K, 10-KSB, 20-F,
11-K, 10-Q,10-QSB, N-SAR, or the transition report or portion thereof, could not
be filed within the prescribed time period. (ATTACH EXTRA SHEETS IF NEEDED)

      The Company changed its independent auditors early this year thereby
creating duplication of efforts that require additional time and effort to
complete the audited financial statements. Further, the Company moved its
business location early this year causing some disruption to the Company's
operation. As a result, the Company has not been able to compile the requisite
audited financial data and other narrative information necessary to enable it to
have sufficient time to complete the Company's Annual Report on Form 10-KSB by
March 31, 2001, the required filing date, without unreasonable effort and
expense.

PART IV--OTHER INFORMATION

(1)   Name and telephone number of person to contact in regard to this
notification

      VINIT SAXENA              (510)                 667-1004
      -------------           -----------        ----------------------------
      (NAME)                  (AREA CODE)        (TELEPHONE NUMBER)

(2)   Have all other periodic reports required under Section 13 or 15(d) of the
Securities Exchange Act of 1934 or Section 30 of the Investment Company Act of
1940 during the preceding 12 months (or for such shorter period that the
registrant was required to file such reports) been filed? If answer is no,
identify report(s). [X] Yes  [ ] No

(3)   Is it anticipated that any significant change in results of operations
from the corresponding period for the last fiscal year will be reflected by the
earnings statements to be included in the subject report or portion thereof?

                    [ ] Yes  [X]  No
      If so, attach an explanation of the anticipated change, both narratively
and quantitatively, and, if appropriate, state the reasons why a reasonable
estimate of the results cannot be made.

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                               SEPRAGEN CORPORATION
                  --------------------------------------------
                  (Name of Registrant as Specified In Charter)

has caused this notification to be signed on its behalf by the undersigned
hereto duly authorized

Dated:  March 30, 2001            SEPRAGEN CORPORATION


                                 By: /s/ Vinit Saxena
                                     ------------------------
                                     Vinit Saxena, CEO

INSTRUCTION: The form may be signed by an executive officer of the registrant or
by any other duly authorized representative. The name and title of the person
signing the form shall be typed or printed beneath the signature. If the
statement is signed on behalf of the registrant by an authorized representative
(other than an executive officer), evidence of the representative's authority to
sign on behalf of the registrant shall be filed with the form.

                                    ATTENTION
      Intention misstatements or omissions of fact constitute Federal Criminal
Violations (See 18 U.S.C. 1001).

                             GENERAL INSTRUCTIONS

1.    This form is required by Rule 12b-25 (17 CFR 240.12b-25) of the General
Rules and Regulations under the Securities Exchange Act of 1934.

2.    One signed original and four conformed copies of this form and amendments
thereto must be completed and filed with the Securities and Exchange Commission,
Washington, D.C. 20549, in accordance with Rule 0-3 of the General Rules and
Regulations under the Act. The information contained in or filed with the form
will be made a matter of public record in the Commission files.

3.    A manually signed copy of the form and amendments thereto shall be filed
with each national securities exchange on which any class of securities of the
registrant is registered.

4.    Amendments to the notifications must also be filed on form 12b-25 but need
not restate information that has been correctly furnished. The form shall be
clearly identified as an amendment notification.

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