Equity-Based Compensation - Activity related to Plans (Details)	6 Months Ended
	Jun. 30, 2016 shares
Employee and Non Employee Stock Option
Stock Options
Outstanding at beginning of period (in shares)	2,904,177
Granted (in shares)	575,409
Exercised (in shares)	(47,937)
Expired and/or forfeited (in shares)	(263,671)
Outstanding at end of period (in shares)	3,167,978
Employee and Non Employee Stock Option | Equity Incentive Plan 2007
Stock Options
Outstanding at beginning of period (in shares)	1,963,162
Granted (in shares)	495,409
Exercised (in shares)	(47,937)
Expired and/or forfeited (in shares)	(152,702)
Outstanding at end of period (in shares)	2,257,932
Employee and Non Employee Stock Option | Stock 2000 Plan
Stock Options
Outstanding at beginning of period (in shares)	14,040
Outstanding at end of period (in shares)	14,040
Employee and Non Employee Stock Option | Lumara Health 2013 Plan
Stock Options
Outstanding at beginning of period (in shares)	96,000
Expired and/or forfeited (in shares)	(41,719)
Outstanding at end of period (in shares)	54,281
Employee and Non Employee Stock Option | Inducement Grants
Stock Options
Outstanding at beginning of period (in shares)	830,975
Granted (in shares)	80,000
Expired and/or forfeited (in shares)	(69,250)
Outstanding at end of period (in shares)	841,725
Employee and Non Employee Restricted Stock Units
Restricted Stock Units
Outstanding at beginning of year (in shares)	654,355
Granted (in shares)	693,826
Vested (in shares)	(247,268)
Forfeited (in shares)	(81,775)
Outstanding at end of year (in shares)	1,019,138
Employee and Non Employee Restricted Stock Units | Equity Incentive Plan 2007
Restricted Stock Units
Outstanding at beginning of year (in shares)	446,330
Granted (in shares)	641,826
Vested (in shares)	(186,521)
Forfeited (in shares)	(68,704)
Outstanding at end of year (in shares)	832,931
Employee and Non Employee Restricted Stock Units | Lumara Health 2013 Plan
Restricted Stock Units
Outstanding at beginning of year (in shares)	52,350
Vested (in shares)	(16,749)
Forfeited (in shares)	(7,571)
Outstanding at end of year (in shares)	28,030
Employee and Non Employee Restricted Stock Units | Inducement Grants
Restricted Stock Units
Outstanding at beginning of year (in shares)	155,675
Granted (in shares)	52,000
Vested (in shares)	(43,998)
Forfeited (in shares)	(5,500)
Outstanding at end of year (in shares)	158,177