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Fair Value Measurements - Contingent Consideration (Details) - USD ($)
$ in Thousands
3 Months Ended 6 Months Ended
Jun. 30, 2016
Jun. 30, 2016
Jun. 30, 2015
Nov. 12, 2014
Reconciliation of contingent consideration obligations related to acquisitions        
Adjustments to fair value of contingent consideration   $ 1,399 $ 1,639  
Lumara Health and MuGard Rights | Fair Value, Measurements, Recurring | Fair Value, Inputs, Level 3        
Reconciliation of contingent consideration obligations related to acquisitions        
Balance at beginning of period   222,559    
Payments made   (149)    
Adjustments to fair value of contingent consideration   1,399    
Balance at end of period $ 223,809 223,809    
Lumara Health        
Reconciliation of contingent consideration obligations related to acquisitions        
Acquisition-related contingent consideration       $ 205,000
Adjustments to fair value of contingent consideration   6,600    
Contingent consideration classified as short term liability 98,300 98,300    
Milestone payment expected to be paid in 2016 to the former Lumara Health security holders based on achievement of a net sales milestone of Makena 100,000 100,000    
Estimated undiscounted milestone amounts payable 350,000 $ 350,000    
Discount rate (as a percent)   5.00%    
MuGard        
Reconciliation of contingent consideration obligations related to acquisitions        
Adjustments to fair value of contingent consideration 5,600 $ (5,200)    
Contingent consideration classified as short term liability 400 $ 400    
Discount rate (as a percent)   9.00%    
Period over which estimated undiscounted royalty amounts could be paid   10 years    
MuGard | Minimum        
Reconciliation of contingent consideration obligations related to acquisitions        
Estimated undiscounted royalty amounts payable 2,000 $ 2,000    
MuGard | Maximum        
Reconciliation of contingent consideration obligations related to acquisitions        
Estimated undiscounted royalty amounts payable 6,000 6,000    
CBR Acquisition Holdings Corp        
Reconciliation of contingent consideration obligations related to acquisitions        
Contingent consideration classified as short term liability $ 0 $ 0