CONDENSED CONSOLIDATED STATEMENTS OF OPERATIONS - USD ($) shares in Thousands, $ in Thousands	3 Months Ended		6 Months Ended
	Jun. 30, 2016	Jun. 30, 2015	Jun. 30, 2016	Jun. 30, 2015
Revenues:
U.S. product sales, net	$ 102,983	$ 84,652	$ 192,547	$ 162,067
Service revenues, net	24,379		43,898
License fee, collaboration and other revenues	57	39,232	273	51,322
Total revenues	127,419	123,884	236,718	213,389
Costs and expenses:
Cost of product sales	21,937	19,679	40,236	40,705
Cost of services	5,195		10,721
Research and development expenses	14,234	8,184	28,463	15,172
Selling, general and administrative expenses	51,924	31,801	115,098	63,913
Impairment charges of intangible assets	15,963		15,963
Acquisition-related costs		2,653		2,653
Restructuring expenses	89	443	712	1,014
Total costs and expenses	109,342	62,760	211,193	123,457
Operating income	18,077	61,124	25,525	89,932
Other income (expense):
Interest expense	(18,250)	(10,205)	(36,693)	(20,572)
Interest and dividend income	773	372	1,481	443
Other income (expense)		2	220	2
Total other income (expense)	(17,477)	(9,831)	(34,992)	(20,127)
Net income (loss) before income taxes	600	51,293	(9,467)	69,805
Income tax expense (benefit)	1,196	18,035	(1,344)	23,643
Net income (loss)	$ (596)	$ 33,258	$ (8,123)	$ 46,162
Net income (loss) per share:
Basic	$ (0.02)	$ 1.09	$ (0.24)	$ 1.60
Diluted	$ (0.02)	$ 0.82	$ (0.24)	$ 1.23
Weighted average shares outstanding used to compute net income (loss) per share:
Basic	34,223	30,636	34,481	28,934
Diluted	34,223	43,181	34,481	40,791