CONDENSED CONSOLIDATED BALANCE SHEETS - USD ($) $ in Thousands	Jun. 30, 2016	Dec. 31, 2015
Current assets:
Cash and cash equivalents	$ 251,110	$ 228,705
Investments	295,359	237,626
Accounts receivable, net	66,086	85,678
Inventories	39,564	40,645
Receivable from collaboration		428
Prepaid and other current assets	13,437	13,592
Total current assets	665,556	606,674
Property, plant and equipment, net	27,173	28,725
Goodwill	639,484	639,188
Intangible assets, net	1,144,858	1,196,771
Restricted cash	2,593	2,593
Other long-term assets	1,146	2,259
Total assets	2,480,810	2,476,210
Current liabilities:
Accounts payable	8,653	4,906
Accrued expenses	107,599	106,363
Current portion of long-term debt	49,610	17,500
Current portion of acquisition-related contingent consideration	98,703	96,967
Deferred revenues	32,499	20,185
Total current liabilities	297,064	245,921
Long-term liabilities:
Long-term debt, net	764,543	803,669
Convertible 2.5% notes, net	174,953	170,749
Acquisition-related contingent consideration	125,106	125,592
Deferred tax liabilities	188,852	189,145
Deferred revenues	9,983	5,093
Other long-term liabilities	4,142	3,777
Total liabilities	1,564,643	1,543,946
Commitments and contingencies
Stockholders' equity:
Preferred stock, par value $0.01 per share, 2,000,000 shares authorized; none issued
Common stock, par value $0.01 per share, 117,500,000 shares authorized; 35,154,044 and 34,733,117 shares issued and outstanding at June 30, 2016 and December 31, 2015, respectively	342	347
Additional paid-in capital	1,224,670	1,233,786
Accumulated other comprehensive loss	(3,058)	(4,205)
Accumulated deficit	(305,787)	(297,664)
Total stockholders' equity	916,167	932,264
Total liabilities and stockholders' equity	$ 2,480,810	$ 2,476,210