CONSOLIDATED BALANCE SHEETS - USD ($) $ in Thousands	Mar. 31, 2016	Dec. 31, 2015
Current assets:
Cash and cash equivalents	$ 203,389	$ 228,705
Investments	276,816	237,626
Accounts receivable, net	82,754	85,678
Inventories	42,002	40,645
Receivable from collaboration	183	428
Prepaid and other current assets	17,089	13,592
Total current assets	622,233	606,674
Property, plant and equipment, net	27,937	28,725
Goodwill	639,484	639,188
Intangible assets, net	1,180,124	1,196,771
Restricted cash	2,593	2,593
Other long-term assets	1,290	2,259
Total assets	2,473,661	2,476,210
Current liabilities:
Accounts payable	3,427	4,906
Accrued expenses	101,895	106,363
Current portion of long-term debt	17,500	17,500
Current portion of acquisition-related contingent consideration	98,436	96,967
Deferred revenues	27,336	20,185
Total current liabilities	248,594	245,921
Long-term liabilities:
Long-term debt, net	800,158	803,669
Convertible 2.5% notes, net	172,822	170,749
Acquisition-related contingent consideration	129,114	125,592
Deferred tax liabilities	188,634	189,145
Deferred revenues	7,659	5,093
Other long-term liabilities	3,708	3,777
Total liabilities	$ 1,550,689	$ 1,543,946
Commitments and contingencies
Stockholders' equity:
Preferred stock, par value $0.01 per share, 2,000,000 shares authorized; none issued
Common stock, par value $0.01 per share, 117,500,000 shares authorized; 34,568,568 and 34,733,117 shares issued and outstanding at March 31, 2016 and December 31, 2015, respectively	$ 346	$ 347
Additional paid-in capital	1,231,090	1,233,786
Accumulated other comprehensive (loss)	(3,273)	(4,205)
Accumulated deficit	(305,191)	(297,664)
Total stockholders' equity	922,972	932,264
Total liabilities and stockholders' equity	$ 2,473,661	$ 2,476,210