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Debt - Convertible Bond Hedge, Warrant Transactions and 2014 Term Loan Facility (Details) - USD ($)
$ / shares in Units, $ in Thousands, shares in Millions
1 Months Ended 3 Months Ended 12 Months Ended
Aug. 17, 2015
Feb. 13, 2014
Aug. 31, 2015
Mar. 31, 2014
Dec. 31, 2015
Dec. 31, 2014
Nov. 30, 2014
Feb. 28, 2014
Feb. 14, 2014
Feb. 11, 2014
Convertible Bond Hedge                    
Common stock covered under convertible bond hedge (in shares)   7.4                
Exercise price (in dollars per unit)   $ 27.09                
Purchase of convertible bond hedges, net of tax       $ 39,800            
Warrant Transactions                    
Number of shares of common stock called by warrants               7.4    
Exercise price (in dollars per share)               $ 34.12    
Exercise price above last reported sale price of common stock (as a percent)               70.00%    
Proceeds from issuance of warrants           $ 25,620        
Sale price of common stock (in dollars per share)                   $ 20.07
Proceeds from Issuance of Warrants           $ 25,620        
2014 Term Loan Facility                    
Loss on debt extinguishment         $ 10,449          
Convertible 2.5% notes                    
Debt                    
Aggregate principal amount of debt issued                 $ 200,000  
2014 Term Loan Facility                    
2014 Term Loan Facility                    
Repayment of debt     $ 323,000              
Loss on debt extinguishment     $ 10,400              
Lumara Health | 2014 Term Loan Facility                    
Debt                    
Aggregate principal amount of debt issued             $ 340,000      
2014 Term Loan Facility                    
Repayment of debt $ 323,000                  
Loss on debt extinguishment         $ 10,400