CONSOLIDATED BALANCE SHEETS - USD ($) $ in Thousands	Dec. 31, 2015	Dec. 31, 2014
Current assets:
Cash and cash equivalents	$ 228,705	$ 119,296
Investments	237,626	24,890
Accounts receivable, net	85,678	38,172
Inventories	40,645	40,610
Receivable from collaboration	428	4,518
Deferred tax assets		32,094
Prepaid and other current assets	13,592	14,456
Total current assets	606,674	274,036
Property, plant and equipment, net	28,725	1,519
Goodwill	639,188	205,824
Intangible assets, net	1,196,771	887,908
Restricted cash	2,593	2,397
Other long-term assets	13,481	17,249
Total assets	2,487,432	1,388,933
Current liabilities:
Accounts payable	4,906	7,301
Accrued expenses	106,363	80,093
Current portion of long-term debt	17,500	34,000
Current portion of acquisition-related contingent consideration	96,967	718
Deferred revenues	20,185	44,376
Total current liabilities	245,921	166,488
Long-term liabilities:
Long-term debt, net	811,250	293,905
Convertible 2.5% notes, net	174,390	167,441
Acquisition-related contingent consideration	125,592	217,984
Deferred tax liabilities	189,145	77,619
Deferred revenues	5,093
Other long-term liabilities	3,777	5,543
Total liabilities	$ 1,555,168	$ 928,980
Commitments and contingencies
Stockholders' equity:
Preferred stock, par value $0.01 per share, 2,000,000 shares authorized; none issued
Common stock, par value $0.01 per share, 117,500,000 shares authorized at December 31, 2015 and 58,750,000 authorized at December 31, 2014; 34,733,117 and 25,599,550 shares issued and outstanding at December 31, 2015 and 2014, respectively	$ 347	$ 256
Additional paid-in capital	1,233,786	793,757
Accumulated other comprehensive (loss)	(4,205)	(3,617)
Accumulated deficit	(297,664)	(330,443)
Total stockholders' equity	932,264	459,953
Total liabilities and stockholders' equity	$ 2,487,432	$ 1,388,933