Equity-Based Compensation (Tables)

9 Months Ended

Sep. 30, 2015

Equity-Based Compensation

Summary of details regarding stock options granted under equity incentive plans

	2007 Equity	2000 Equity	2013 Lumara
	Plan	Plan	Equity Plan	Total
Outstanding at December 31, 2014	2,051,017	35,266	44,000	2,130,283
Granted	840,475	—	76,000	916,475
Exercised	(652,181)	(21,226)	—	(673,407)
Expired or terminated	(257,146)	—	—	(257,146)
Outstanding at September 30, 2015	1,982,165	14,040	120,000	2,116,205

Summary of details regarding restricted stock units granted under equity incentive plans

	2007 Equity	2000 Equity	2013 Lumara
	Plan	Plan	Equity Plan	Total
Outstanding at December 31, 2014	360,826	—	20,000	380,826
Granted	253,954	—	60,225	314,179
Vested	(72,832)	—	—	(72,832)
Expired or terminated	(95,243)	—	(2,875)	(98,118)
Outstanding at September 30, 2015	446,705	—	77,350	524,055

Schedule of equity-based compensation expense

	Three Months Ended September 30,				Nine Months Ended September 30,
	2015		2014		2015		2014
Cost of product sales	$	159	$	32	$	254	$	89
Research and development		1,028		466		2,071		1,274
Selling, general and administrative		3,701		1,448		9,247		4,790
Total equity-based compensation expense	$	4,888	$	1,946	$	11,572	$	6,153
Income tax effect		(871)		—		(3,464)		—
After-tax effect of equity-based compensation expense	$	4,017	$	1,946	$	8,108	$	6,153