Inventories (Details) (USD $) In Thousands, unless otherwise specified	1 Months Ended	9 Months Ended
	May 31, 2013 item	Sep. 30, 2013	Sep. 30, 2012	Dec. 31, 2012
Inventories
Raw materials		$ 5,151		$ 2,652
Work in process		5,835		2,524
Finished goods		3,708		7,275
Total inventories		14,694		12,451
Number of specific batches of Rienso recalled by Takeda	1
Inventory expensed		$ 502	$ 598