CONDENSED CONSOLIDATED STATEMENTS OF OPERATIONS (USD $) In Thousands, except Per Share data, unless otherwise specified	3 Months Ended
	Mar. 31, 2013	Mar. 31, 2012
Revenues:
U.S. product sales, net	$ 15,578	$ 13,626
International product sales and royalties	63
License fee and other collaboration revenues	2,003	1,753
Other product sales and royalties	236	101
Total revenues	17,880	15,480
Costs and expenses:
Cost of product sales	2,942	2,646
Research and development expenses	5,404	12,462
Selling, general and administrative expenses	14,005	13,181
Total costs and expenses	22,351	28,289
Other income (expense):
Interest and dividend income, net	271	393
Gains on sale of assets held for sale	299
Gains on investments, net	6
Total other income (expense)	576	393
Net loss	$ (3,895)	$ (12,416)
Net loss per share:
Basic and diluted (in dollars per share)	$ (0.18)	$ (0.58)
Weighted average shares outstanding used to compute net loss per share:
Basic and diluted (in shares)	21,544	21,349