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Summary of Significant Accounting Policies (Details 4) (USD $)
12 Months Ended
Dec. 31, 2013
Dec. 31, 2012
Dec. 31, 2011
Dec. 31, 2010
Dec. 31, 2013
Sales Revenue, Net
Revenue Concentration Risk
AmerisourceBergen Drug Corporation.
Dec. 31, 2012
Sales Revenue, Net
Revenue Concentration Risk
AmerisourceBergen Drug Corporation.
Dec. 31, 2011
Sales Revenue, Net
Revenue Concentration Risk
AmerisourceBergen Drug Corporation.
Dec. 31, 2013
Sales Revenue, Net
Revenue Concentration Risk
McKesson Corporation
Dec. 31, 2012
Sales Revenue, Net
Revenue Concentration Risk
McKesson Corporation
Dec. 31, 2011
Sales Revenue, Net
Revenue Concentration Risk
McKesson Corporation
Dec. 31, 2013
Sales Revenue, Net
Revenue Concentration Risk
Cardinal Health, Inc
Dec. 31, 2012
Sales Revenue, Net
Revenue Concentration Risk
Cardinal Health, Inc
Dec. 31, 2011
Sales Revenue, Net
Revenue Concentration Risk
Cardinal Health, Inc
Dec. 31, 2013
Sales Revenue, Net
Revenue Concentration Risk
Takeda Pharmaceutical Company Limited (outside the U.S.)
Dec. 31, 2012
Sales Revenue, Net
Revenue Concentration Risk
Takeda Pharmaceutical Company Limited (outside the U.S.)
Dec. 31, 2011
Sales Revenue, Net
Revenue Concentration Risk
Takeda Pharmaceutical Company Limited (outside the U.S.)
Dec. 31, 2013
Sales Revenue, Net
Revenue Concentration Risk
GPO
Dec. 31, 2012
Sales Revenue, Net
Revenue Concentration Risk
GPO
Dec. 31, 2011
Sales Revenue, Net
Revenue Concentration Risk
GPO
Dec. 31, 2013
Sales Revenue, Net
Geographical Concentration Risk
Dec. 31, 2012
Sales Revenue, Net
Geographical Concentration Risk
Dec. 31, 2011
Sales Revenue, Net
Geographical Concentration Risk
Investment Concentration Risk                                            
Cash, cash equivalents and investments $ 213,800,000                                          
Investment in institutional money market funds 18,800,000                                          
Cash and cash equivalents 26,986,000 46,293,000 63,474,000 112,646,000                                    
Amount invested in a single money market fund collateralized by U.S. treasury and government agency securities $ 12,200,000                                          
Customers representing 10% or more of revenues                                            
Percentage of revenues from major customer         41.00% 34.00% 41.00% 24.00% 17.00% 21.00% 16.00% 12.00% 13.00% 11.00% 31.00% 13.00% 30.00% 32.00% 35.00%      
Percentage of revenues From customers outside of the U.S.                                            
Approximate percentage of revenues from customers outside the U.S.                                       11.00% 32.00% 14.00%