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Inventories (Details) (USD $)
12 Months Ended
Dec. 31, 2012
Dec. 31, 2011
Dec. 31, 2012
Cost of goods sold
Dec. 31, 2012
Research and development expenses
Dec. 31, 2012
Restructuring costs
Dec. 31, 2012
Minimum
U.S.
Dec. 31, 2012
Minimum
Outside U.S.
Dec. 31, 2012
Maximum
U.S.
Dec. 31, 2012
Maximum
Outside U.S.
Major classes of inventories                  
Raw materials $ 2,652,000 $ 1,892,000              
Work in process 2,524,000 3,696,000              
Finished goods 7,275,000 9,618,000              
Total inventories 12,451,000 15,206,000              
Shelf-life of Feraheme/Rienso                  
Shelf-life of Feraheme/Rienso           4 years 2 years 5 years 3 years
Inventory write-off     $ 600,000 $ 600,000 $ 700,000