Summary of Significant Accounting Policies (Details 3) (USD $)	12 Months Ended
Dec. 31, 2012
Assets held for sale
Fair market value of assets held for sale	$ 2,000,000
Accelerated depreciation of assets held for sale	1,400,000
Impairment loss	1,100,000
Non-cash charges	2,500,000
Cost of product sales
Assets held for sale
Non-cash charges	2,300,000
Research and development
Assets held for sale
Non-cash charges	$ 200,000

The aggregate amount of write-downs for impairments recognized during the period for long-lived assets held for abandonment, exchange or sale.

Reference 1: http://www.xbrl.org/2003/role/presentationRef

-Publisher FASB

-Name Accounting Standards Codification

-Topic 230

-SubTopic 10

-Section 45

-Paragraph 28

-Subparagraph (b)

-URI http://asc.fasb.org/extlink&oid=6943989&loc=d3e3602-108585

Reference 2: http://www.xbrl.org/2003/role/presentationRef

-Publisher FASB

-Name Accounting Standards Codification

-Topic 360

-SubTopic 10

-Section 45

-Paragraph 15

-URI http://asc.fasb.org/extlink&oid=8077374&loc=d3e2611-110228

Reference 3: http://www.xbrl.org/2003/role/presentationRef

-Publisher FASB

-Name Statement of Financial Accounting Standard (FAS)

-Number 144

-Paragraph 27, 28, 29, 30

-LegacyDoc This reference is SUPERSEDED by the Accounting Standards Codification effective for interim and annual periods ending after September 15, 2009. This reference is included to help users transition from the previous accounting hierarchy and will be removed from future versions of this taxonomy.

Name:	us-gaap_ImpairmentOfLongLivedAssetsToBeDisposedOf
Namespace Prefix:	us-gaap_
Data Type:	xbrli:monetaryItemType
Balance Type:	debit
Period Type:	duration