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Current and Long-Term Liabilities (Tables)
12 Months Ended
Dec. 31, 2012
Current and Long-Term Liabilities  
Schedule of accrued expenses

Accrued expenses consisted of the following as of December 31, 2012 and 2011 (in thousands):

 
  December 31,  
 
  2012   2011  

Clinical, manufacturing and regulatory consulting fees and expenses

  $ 7,737   $ 11,468  

Salaries, bonuses, and other compensation

    5,236     5,924  

Commercial rebates, fees and returns

    3,448     5,943  

Professional, license, and other fees and expenses

    1,719     1,966  

Restructuring expense

    1,383     2,366  

Commercial consulting fees and expenses

    815     1,249  
           

Total accrued expenses

  $ 20,338   $ 28,916  
           
Schedule of deferred revenues

Deferred revenues consisted of the following as of December 31, 2012 and 2011 (in thousands):

 
  December 31,  
 
  2012   2011  

Short-term deferred revenues:

             

Takeda

  $ 8,854   $ 6,096  

Other short-term deferred revenues

    250     250  
           

Total

  $ 9,104   $ 6,346  
           

Long-term deferred revenues:

             

Takeda

  $ 49,350   $ 44,196  

3SBio

    1,000     1,000  
           

Total

  $ 50,350   $ 45,196