CONDENSED CONSOLIDATED STATEMENTS OF CASH FLOWS - USD ($) $ in Thousands	9 Months Ended
	Sep. 30, 2020	Sep. 30, 2019
Cash flows from operating activities:
Net loss	$ (31,466)	$ (267,509)
Adjustments to reconcile net loss to net cash used in operating activities:
Depreciation and amortization	22,276	13,871
Impairment of intangible assets	0	77,358
Provision for bad debt expense	230	(12)
Amortization of premium/discount on purchased securities	94	(64)
Write-down of inventory	1,916	4,872
Loss on disposal of property & equipment	273	0
Non-cash equity-based compensation expense	8,100	14,381
Non-cash IPR&D expense	0	18,029
Amortization of debt discount and debt issuance costs	12,300	11,332
Gains on marketable securities, net	(10)	(263)
Change in fair value of contingent consideration	0	(16)
Deferred income taxes	630	408
Non-cash lease expense	1,416	0
Gain on sale of assets	7,047	0
Changes in operating assets and liabilities:
Accounts receivable, net	26,328	(2,229)
Inventories	(676)	(6,824)
Prepaid and other current assets	(5,797)	(24,075)
Accounts payable and accrued expenses	(58,258)	54,073
Deferred revenues	9,461	(101)
Other assets and liabilities	(627)	1,038
Net cash used in operating activities	(6,763)	(105,731)
Cash flows from investing activities:
Proceeds from sales or maturities of marketable securities	43,675	85,321
Purchase of marketable securities	(55,763)	(14,815)
Milestone payment for Vyleesi developed technology	0	(60,000)
Net proceeds from the sale of assets	4,920	0
Capital expenditures	(475)	(2,098)
Net cash (used in) provided by investing activities	(7,643)	8,408
Cash flows from financing activities:
Payments to settle convertible notes	0	(21,417)
Payments of contingent consideration	(17)	(50)
Payments for repurchases of common stock	0	(13,730)
Proceeds from the issuance of common stock under the ESPP	630	851
Proceeds from the exercise of common stock options	168	30
Payments of employee tax withholding related to equity-based compensation	(1,400)	(1,817)
Net cash used in financing activities	(619)	(36,133)
Net decrease in cash, cash equivalents, and restricted cash	(15,025)	(133,456)
Cash, cash equivalents, and restricted cash at beginning of the period	113,504	253,751
Cash, cash equivalents, and restricted cash at end of the period	98,479	120,295
Supplemental data for cash flow information:
Cash (refunded) paid for taxes	(254)	456
Cash paid for interest	5,200	5,467
Non-cash investing and financing activities:
Settlement of note receivable in connection with Perosphere acquisition	0	10,000
Right-of-use assets obtained in exchange for lease liabilities	$ 0	$ 918