Revenue Recognition - Total Gross Product (Details) - USD ($) $ in Thousands	3 Months Ended		6 Months Ended
	Jun. 30, 2020	Jun. 30, 2019	Jun. 30, 2020	Jun. 30, 2019
Provision for product sales allowances and accruals:
Revenues	$ 52,755	$ 77,767	$ 123,200	$ 153,255
Product Revenue
Disaggregation of Revenue [Line Items]
Gross product sales	181,995	239,185	414,735	450,904
Provision for product sales allowances and accruals:
Contractual adjustments	109,861	128,641	253,036	237,526
Governmental rebates	19,405	32,910	38,557	60,331
Total	129,266	161,551	291,593	297,857
Revenues	$ 52,729	$ 77,634	$ 123,142	$ 153,047