CONDENSED CONSOLIDATED STATEMENTS OF OPERATIONS - USD ($) shares in Thousands, $ in Thousands	3 Months Ended
	Mar. 31, 2020	Mar. 31, 2019
Revenues:
Revenues	$ 68,661	$ 75,804
Costs and expenses:
Cost of product sales	24,359	18,477
Research and development expenses	11,180	18,066
Acquired in-process research and development	0	74,856
Selling, general and administrative expenses	52,697	74,682
Restructuring expenses	0	7,420
Total costs and expenses	88,236	193,501
Operating loss	(19,575)	(117,697)
Other income (expense):
Interest expense	(6,604)	(6,450)
Interest and dividend income	477	1,586
Other income	1,311	340
Total other expense, net	(4,816)	(4,524)
Loss before income taxes	(24,391)	(122,221)
Income tax expense (benefit)	100	(137)
Net loss	$ (24,491)	$ (122,084)
Basic and diluted net loss per share (in dollars per share)	$ (0.72)	$ (3.54)
Weighted average shares outstanding used to compute net loss per share (basic and diluted) (in shares)	34,104	34,469
Product Sales
Revenues:
Revenues	$ 68,628	$ 75,729
Other revenues
Revenues:
Revenues	$ 33	$ 75