Equity-Based Compensation (Tables)

9 Months Ended

Sep. 30, 2019

Share-based Payment Arrangement [Abstract]

Summary of details regarding stock option activity

The following table summarizes stock option activity for the nine months ended September 30, 2019:

	2019 Equity	2007 Equity		2013 Lumara		Inducement
	Plan	Plan		Equity Plan		Grants		Total
Outstanding at December 31, 2018	—	2,781,786		124,450		810,343		3,716,579
Granted	344,208	465,009		34,700		80,366		924,283
Exercised	—	(2,025	)	—		—		(2,025	)
Expired or terminated	—	(585,312	)	(26,275	)	(131,250	)	(742,837	)
Outstanding at September 30, 2019	344,208	2,659,458		132,875		759,459		3,896,000

Summary of details regarding restricted stock activity

The following table summarizes RSU activity for the nine months ended September 30, 2019:

	2019 Equity		2007 Equity		2013 Lumara		Inducement
	Plan		Plan		Equity Plan		Grants		Total
Outstanding at December 31, 2018	—		1,041,141		2,101		85,293		1,128,535
Granted	123,228		1,023,847		1,100		29,385		1,177,560
Vested	—		(354,563	)	(1,034	)	(44,909	)	(400,506	)
Expired or terminated	(1,800	)	(250,968	)	—		(7,500	)	(260,268	)
Outstanding at September 30, 2019	121,428		1,459,457		2,167		62,269		1,645,321

Schedule of equity-based compensation expense

Equity-based compensation expense for the three and nine months ended September 30, 2019 and 2018 consisted of the following (in thousands):

	Three Months Ended September 30,				Nine Months Ended September 30,
	2019		2018		2019		2018
Cost of product sales	$	225	$	281	$	626	$	588
Research and development	691		568		2,051		1,896
Selling, general and administrative	4,058		4,202		11,039		12,149
Total equity-based compensation expense	4,974		5,051		13,716		14,633
Income tax effect	—		—		—		—
After-tax effect of equity-based compensation expense	$	4,974	$	5,051	$	13,716	$	14,633